Benign Thyroid Nodule, Quality of Life
Conditions
Brief summary
To detect any changes in Quality of Life in patients with benign thyroid diseases who undergo thyroidectomy compared to patients with benign thyroid diseases and conservative treatment and healthy subjects.
Detailed description
Benign thyroid diseases are a common public health problem. It has been reported that thyroid diseases can affect Quality of Life (QoL), but this is not easy to be assessed. Therefore, a valid instrument is necessary. Such an instrument is Thyroid-related patient-reported outcomes questionnaire (ThyPRO). ThyPRO has been recently translated and validated in Greek language. The questionnaire consists of 85 items grouped in 14 scales concerning goiter, hypothyroidism, hyperthyroidism and eye symptoms, tiredness, cognitive impairment, anxiety, depression, emotional susceptibility, cosmetic complaints and impaired social, and daily and sex life, as well as overall quality of life. A few studies have demonstrated that various thyroid therapies may improve some aspects of QoL. The aim of the present study is to address the impact of thyroidectomy in QoL in patients with benign thyroid diseases.
Interventions
PROCEDUREThyroidectomy
Thyroidectomy
Sponsors
Aristotle University Of Thessaloniki
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
1. Patient is over 18 years old 2. Patient scheduled for a non-emergency operation 3. Patient diagnosed with benign thyroid disease
Exclusion criteria
1. Patient is participating in another clinical trial which may affect this study's outcomes 2. Patient with thyroid cancer 3. Previous operation at the thyroid and parathyroid glands or neck irradiation 4. Patient unable to read and write in Greek
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Alterations in Quality of Life after thyroidectomy for benign thyroid disease | 2 years | To detect any changes in Quality of Life in patients with benign thyroid diseases who undergo thyroidectomy compared to patients with benign thyroid diseases and conservative treatment. The Greek, cross-cultural validated, version of ThyPRO questionnaire will be used, as it comprises a reliable and validated instrument to measure thyroid-related quality of life. The 84 questions of ThyPRO are categorized in 13 scales that involve: goiter, hypothyroidism, hyperthyroidism and eyes symptoms, tiredness, cognitive impairment, anxiety, depressivity, emotional susceptibility, cosmetic complaints and impaired social, and daily and sex life. The scales are all scored and the final scores were transformed to a scale from 0 to 100. Lower scores reflect a better thyroid-related quality of life, whereas higher scores reflect a worse quality of life. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Correlation of alterations in Quality of Life after thyroidectomy for benign thyroid disease with secondary characteristics of the patients | 2 years | Correlation of alterations in Quality of Life after thyroidectomy for benign thyroid disease with secondary characteristics of the patients ( eg age, thyroid autoimmunity, thyroid function, Vitamin D levels) |
Countries
Greece
Outcome results
None listed