Type 2 Diabetes Mellitus
Conditions
Keywords
Tai Chi Quan, HbA1c, quality of life
Brief summary
In this study, the hypothesis that the 12-week Tai Chi Quan training would have better control of blood sugar, biochemistry profile, and also better quality of life and activity of autonomic nerve system (ANS). The subjects were randomize assigned to either Tai Chi group or control group. The outcome measures before and after 12-week intervention include basic demographic characteristics, HbA1c, fasting blood glucose(FBG), triglycerides (TG), high and low density lipoprotein (HDL, LDL), creatinine(Cr), eGFR, GPT, ACR, quality of life, and activity of automatic nerve system.
Detailed description
In this study, the hypothesis that the 12-week Tai Chi Quan training would have better control of blood sugar, biochemistry index, and also better quality of life and activity of automatic nerve system. In the study, type 2 diabetes mellitus(T2DM) patients will be recruited as subjects. The subjects were randomized to either Tai Chi group or control group. Tai Chi group would take Tai Chi Quan training for 1hr, twice a week for 12 weeks. There were 10-minute warm-up, 40-minute Tai Chi lesson, and 10-minute cool-down exercise in the training. In this study, the 1st section of Yang style 108 form is chosen for the experiment group. Both group were given diabetic patients care education and the exercise recording book for encouraging the daily exercise habits. The outcome measures before and after 12-week intervention include basic demographic characteristics, HbA1c, fasting blood glucose, triglycerides, high and low density lipid, creatinine, eGFR, GPT, ACR, quality of life, and activity of automatic nerve system.
Interventions
BEHAVIORALTai Chi Quan
the first section of Yang style 108 form, including 10-minute warm-up, 40-minute training, and 10-minute cool-down exercise, twice a week
Sponsors
National Yang Ming Chiao Tung University
Taipei City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 40\ 80 years old * Diagnosed type 2 diabetes mellitus, and without changing dietary pattern and medical treatment for blood glucose or blood lipid. * Consciousness clear and is voluntary to attend the project and with the agreement. * The functional movement ability is independent
Exclusion criteria
* Pregnant or plan to be pregnant in six months, and breast feeding. * Severe complication in six months such as myocardial infarction, stroke, severe traumatic injury, major surgery. Other diseases evaluated by the doctor that are not suitable for the project. * Evaluated that the compliance for the intervention is not appropriate. * The blood glucose \> 300mg/dl and unable to do vigorous exercise.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hemoglobin | change from Baseline to 12 weeks | HbA1c |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| triglycerides | change from Baseline to 12 weeks | blood sample after 8-hour fasting |
| high and low density lipoprotein | change from Baseline to 12 weeks | blood sample after 8-hour fasting |
| creatinine | change from Baseline to 12 weeks | blood sample after 8-hour fasting |
| estimated Glomerular Filtration Rate (eGFR) | change from Baseline to 12 weeks | blood sample after 8-hour fasting |
| Glutamic-Pyruvic Transaminase (GPT) | change from Baseline to 12 weeks | blood sample after 8-hour fasting |
| fasting blood glucose | change from Baseline to 12 weeks | blood sample after 8-hour fasting |
| quality of life | change from Baseline to 12 weeks | WHOQOL-BREF Taiwan |
| heart rate variability | change from Baseline to 12 weeks | represent for balance of autonomic nervous system |
| low frequency (LF) | change from Baseline to 12 weeks | Low frequency is the frequency domain analysis from heart rate variability, and is represent for sympathetic nervous system |
| high frequency (HF) | change from Baseline to 12 weeks | High frequency is the frequency domain analysis from heart rate variability, and is represent for parasympathetic nervous system |
| urine albumin/creatinine ratio (ACR) | change from Baseline to 12 weeks | from urine sample |
Countries
Taiwan
Contacts
Primary ContactChien-Jung Huang, Bachelor
Outcome results
None listed