Nutrition, Performance, Protein
Conditions
Brief summary
Twenty-four well trained runners (VO2max 60.73.7 ml O2 Kg-1 min1) completed a six week block randomized controlled intervention period. Subjects were randomly assigned to either PRO-CHO or CHO and matched in pairs for gender, age, VO2max, training and performance status. The PRO- CHO group ingested a protein beverage (0.3g kg-1) before and protein-carbohydrate beverage (0.3g protein kg-1 and 0.1g carbohydrate kg-1) after each exercise session. The CHO group ingested energy matched carbohydrate. Post-absorptive muscle biopsies were obtained pre and post intervention for analysis HAD, CS and PGC-1. Subjects completed two physical tests 6 km performance test (pre, week 1 and week 6) and aVo2max test (pre and post intervention).
Interventions
DIETARY_SUPPLEMENTPROTEIN-CARBOHYDRATE
PRO before and PRO-CHO after training
DIETARY_SUPPLEMENTCARBOHDYRATE
CHO before and after training
Sponsors
University of Aarhus
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Subject)
Masking description
Single blinded
Intervention model description
block randomized controlled intervention
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
1. maximal oxygen uptake (VO2max) of \>50ml O2 kg-1 min-1 for women and \>55ml O2 kg-1 min-1 for men, 2. running at least 3 times a week and 3. running being the primarily training form
Exclusion criteria
1. use of medicine 2. diagnosed metabolic diseases 3. injuries which hindered running and body mass index (BMI) \< 25 kg m-2
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Maximal oxygen uptake | Change from week 1 to week 6 | maximal oxygen uptake (L O2/min) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Performance | Change from week 1 to week 6 | 6 km trial test |
| VDAC | Change from week 1 to week 6 | Mitochondria target measured by western blotting |
| CytC | Change from week 1 to week 6 | Mitochondria enzyme measured by western blotting |
| HSP60 | Change from week 1 to week 6 | Mitochondria target measured by western blotting |
| CD36 | Change from week 1 to week 6 | Fat transporter measured by western blotting |
| COX-IV | Change from week 1 to week 6 | Mitochondria target measured by western blotting |
Countries
Denmark
Outcome results
None listed