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Evaluation of the Dosing Regimen of Vancomycin in Pediatric Patients

Evaluation of the Dosing Regimen of Vancomycin in Pediatric Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03560440
Enrollment
368
Registered
2018-06-18
Start date
2014-06-30
Completion date
2017-06-30
Last updated
2018-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gram-Positive Bacterial Infections

Keywords

Vancomycin, Pharmacokinetics, Trough level, Pediatric

Brief summary

In this retrospective registry the investigators wish to verify whether the current dosing regime of vancomycin is leading to the appropriate pharmacokinetic targets in pediatric patients. Therefore data will be collected from all pediatric patients hospitalized in University Hospitals Leuven between January 2012 and April 2014 who were treated with vancomycine.

Detailed description

In this retrospective registry the investigators wish to verify whether the current dosing regime of vancomycin is leading to the appropriate pharmacokinetic targets in pediatric patients. Therefore data will be collected from all pediatric patients hospitalized in University Hospitals Leuven between January 2012 and April 2014 who were treated with vancomycine. Patient files will be screened for relevant information. Individual patients can be included multiple times if vancomycin has been administered more than once.

Interventions

OTHERPlasma exposure vancomycin

Investigation of plasma exposure of vancomycin.

Sponsors

Universitaire Ziekenhuizen KU Leuven
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Pediatric patients hospitalized in the University Hospitals Leuven between January 2012 and April 2014, treated with vancomycin

Exclusion criteria

\-

Design outcomes

Primary

MeasureTime frameDescription
Loading dose related plasma exposure vancomycin24 hours after loading dosePlasma exposure to vancomycin in relation to administered dose

Other

MeasureTime frameDescription
Loading dose related plasma exposure vancomycin24 hours after dosage adjustmentPlasma exposure to vancomycin in relation to administered dose

Countries

Belgium

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026