Acquired Brain Injury, Cognitive Symptom, Executive Dysfunction
Conditions
Brief summary
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury
Detailed description
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury using two clinically developed programmes and one sham-intervention. Furthermore, the study consists of Groups that receives the computerized training both with and witouth support from a professional.
Interventions
OTHERSham computerized gaming
Sham training with generally stimulating computer-games
BEHAVIORALComputer based cognitive rehabilitation
Computer based cognitive rehabilitation is a supplementary computerized tool for cognitive rehabilitation design to train various cognitive functions. Many programmes are available. The current study investigates the effects on two such programmes on rehabilitation of executive functions in the chronic phase after acquired brain injury.
Sponsors
University of Copenhagen
Katrine Sværke
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Patients know that one of the conditions is a control-condition not expected to have significant clinical effects (required by the danish scientific committee), but they don't know which treatment condition they are randomised to. The outcome assessor is blind to the group allocation of patients.
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Persons who are able to give an informed consent both verbally and in writing * Persons in the chronic phase after stroke or traumatic brain injury (more than one year post onset) * Persons who score less than the 30. Percentile in one or more of the primary outcome measures outlined above.
Exclusion criteria
* Persons with neurodegenerative diseases * Persons with diseases which can influence executive functions such as ADHD * Persons who are motorically or cognitively unable to use a tablet and complete the CBCR-training
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| PASAT | 3 seconds | Paced auditory serial addition test, test of verbal working memory |
| Trail making test A+B | 5 minutes | Trail test A: Test of visual attention, trail test B: Test of visual working memory and cognitive shifts |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Digit span (WAIS-IV) | 5 minutes | Test of verbal memory (forward) and working memory (backward) |
| Spatial span (WMS-III) | 5 minutes | Test of visuospatial memory (forward) and visuospatial working memory (backward) |
| Stroop colour and word test | 3 minutes | Test of inhibition |
| SDMT | 90 seconds | Symbol digit modalities test: Test of processing speed |
| Quality of Life after Brain Injury (QOLIBRI) | 10 minutes | Questionnaire about quality of life |
| Wordlist, Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) | 10 minutes | Verbal memory test |
| BNI-FS | 10 minutes | Barrow Neurological Institute Fatigue Scale: Test of fatigue after brain injury |
| Word fluency test | 1 min | Test of verbal fluency |
Countries
Denmark
Outcome results
None listed