Hypotension, Spinal Anesthetics Causing Adverse Effects in Therapeutic Use
Conditions
Brief summary
This observational study is to evaluate Perfusion Index Change as a Predictor of Hypotension During Propofol Sedation in Adult Patients Undergoing Hip Surgery Under Spinal Anesthesia.
Interventions
OTHERObservation
no intervention
Sponsors
Samsung Medical Center
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
19 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Adult patients having hip surgery under spinal anesthesia and propofol sedation
Exclusion criteria
* ASA class IV or above * pregnancy * inability to measure noninvasive blood pressure on the arm * preexisting hemodynamic instability * known peripheral artery occlusive disease * known autonomic nerve dysfunction * uncontrolled hypertension
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 10-minute perfusion index | After sedation until start of surgery (an average of 20 minutes) | ability of perfusion index 10 minutes after induction in predicting propofol sedation-induced hypotension |
| 5-minute perfusion index change | After sedation until start of surgery (an average of 20 minutes) | ability of perfusion index change 5 minutes after induction in predicting propofol sedation-induced hypotension (perfusion index change is calculated as the percent change from baseline values) |
| 10-minute perfusion index change | After sedation until start of surgery (an average of 20 minutes) | ability of perfusion index change 10 minutes after induction in predicting propofol sedation-induced hypotension (perfusion index change is calculated as the percent change from baseline values) |
| baseline perfusion index | After sedation until start of surgery (an average of 20 minutes) | ability of baseline perfusion index in predicting propofol sedation-induced hypotension |
| 5-minute perfusion index | After sedation until start of surgery (an average of 20 minutes) | ability of perfusion index 5 minutes after induction in predicting propofol sedation-induced hypotension |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| 5-minute perfusion index change difference | After sedation until start of surgery (an average of 20 minutes) | difference of perfusion index change 5 minutes after induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia (perfusion index change is calculated as the percent change from baseline values) |
| 10-minute perfusion index change difference | After sedation until start of surgery (an average of 20 minutes) | difference of perfusion index change 10 minutes after induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia (perfusion index change is calculated as the percent change from baseline values) |
| baseline perfusion index difference | After sedation until start of surgery (an average of 20 minutes) | difference of baseline perfusion index between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia |
| 5-minute perfusion index difference | After sedation until start of surgery (an average of 20 minutes) | difference of perfusion index after 5 minutes of induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia |
| 10-minute perfusion index difference | After sedation until start of surgery (an average of 20 minutes) | difference of perfusion index after 10 minutes of induction between participants who do or do not develop hypotension during propofol sedation after spinal anesthesia |
Countries
South Korea
Outcome results
None listed