Extracorporeal Membrane Oxygenation
Conditions
Keywords
fluid responsiveness, trendelenburg, extracorporeal membrane oxygenation
Brief summary
The purpose of the study is to verify the efficacy of using trendelenburg maneuver to predict fluid responsiveness in patients with extracorporeal membrane oxygenation
Interventions
DIAGNOSTIC_TESTTrendelenburg Maneuver
In the Trendelenburg position, the body is laid supine, or flat on the back with the feet higher than the head by 15-30 degrees. The venous return increases in the trendelenburg position which in turn increases the stroke volume.
Sponsors
Shanghai Zhongshan Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* patients with ECMO and mechanical ventilator support * hypotension (MAP\<65mmHg) * required volume expansion by clinical judgement of the intensivists
Exclusion criteria
* severe hypotension with high dose of vasopressors * severe valve regurgitation * cardiac arrhythmia
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| responders | within 1 minute after volume expansion | responders are defined by stroke volume increases over 15% after volume expansion of 500ml crystalloid |
| nonresponders | within 1 minute after volume expansion | nonresponders are defined by stroke volume increases less than 15% after volume expansion of 500ml crystalloid |
Countries
China
Contacts
Primary ContactGuo-wei Tu, Doctor
Outcome results
None listed