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Pulmonary and Upper Limb Functions in Duchenne Muscular Dystrophy

The Comparison of Pulmonary and Upper Extremity Functions Between Children With Duchenne Muscular Dystrophy and Healthy Peers

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03552874
Enrollment
47
Registered
2018-06-12
Start date
2017-01-01
Completion date
2018-03-31
Last updated
2018-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Duchenne Muscular Dystrophy, Respiratory Function Test, Upper Limb Function

Brief summary

Although it is known that the functions of pulmonary and upper limb is affected in late stage of Duchenne Muscular Dystrophy (DMD) negatively, the investigators do not have clear information about its early stage. The aim of this study was to investigate the differences in pulmonary and upper limb functions between children with DMD in early stage and healthy peers.

Interventions

OTHERThe Performance of Upper Limb Questionnaire (PUL)

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
5 Years to 10 Years
Healthy volunteers
Yes

Inclusion criteria

children with DMD was; * age between 5-10 years * being on treatment with corticosteroids for more than 6 months * being at Level I according to Brooke Upper and Lower Extremity Classification Systems Healthy peers; * age between 5-10 years * not having any diagnosed disease

Exclusion criteria

• Children has undergo surgery and disease affect upper extremity or pulmonary function in last six months.

Design outcomes

Primary

MeasureTime frameDescription
Pulmonary Function Test (PFT)5 minutesThe pulmonary function tests of the participants were evaluated with a spirometry. The child was asked to perform the spirometric tests for three times with maximum effort. The child was motivated before each attempt for stronger and longer expiration.The result of Pulmonary function Test were recorded.
The Performance Upper Limb (PUL)15 minutesUpper limb functions of participants were evaluated with The Performance of Upper Limb (PUL) scale. This scale, which was shown to be reliable in DMD, has 22 items in total. It consists of 3 different levels of function: high, mid, and distal. PUL also has four items determining timed performance.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026