Type1diabetes
Conditions
Brief summary
This study aimed to use a multi-disciplinary approach to evaluate a 6-week home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
Detailed description
This study aimed to use a multi-disciplinary approach to evaluate a home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes. Eleven individuals with type 1 diabetes (4 men/7 women; age 30±3 years; BMI 27.1±1.2 kg·m-2; V ̇O2peak 32.4±2.1 ml∙kg∙min-1; duration of type 1 diabetes 10±2 years) completed six weeks of Home-HIT. The effect of Home-HIT on V ̇O2peak, blood pressure, insulin dose and glycaemic profile was assessed pre and post-training. Adherence and ability to meet target heart rate (HR) thresholds (compliance) were monitored using a HR monitor and mobile phone application. Change in glycaemia was measured pre, post and 1h post exercise sessions throughout the six-week period. A qualitative online survey was completed post-training. This is the first study to combine physiological outcomes with a qualitative evaluation of a training intervention in people with type 1 diabetes. Home-HIT resulted in high adherence alongside increased V ̇O2peak and decreased insulin dose. Because Home-HIT is time-efficient and removes barriers to exercise including fear of hypoglycaemia, it may represent an effective strategy to increase exercise participation in people with type 1 diabetes.
Interventions
BEHAVIORALHome-HIT
Participants completed 6 weeks of home-based high-intensity interval training 3 times per week
Sponsors
Liverpool John Moores University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No
Inclusion criteria
* duration of type 1 diabetes \>6 months, * no significant history of hyper- or hypoglycaemia
Exclusion criteria
* duration of type 1 diabetes \<6 months, * significant history of hyper- or hypoglycaemia, * pregnancy or planning pregnancy, * uncontrolled hypertension (\>180/100 mmHg), * angina * autonomic neuropathy, * taking any medication that affects heart rate (HR) * major surgery planned within 6 weeks of the study * severe nonproliferative * unstable proliferative retinopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in maximal aerobic capacity | change in baseline maximal aerobic capacity at 6 weeks | Maximal aerobic capacity was measured pre and post 6 week training intervention using a MOXUS gas analyser on a stationary cycle ergometer |
| adherence over the course of the training programme | adherence to the training programme over the course of the 6 week intervention | session completion rate (adherence) was assessed |
| Compliance over the course of the training programme | compliance to the training programme over the course of the 6 week intervention | ability to meet target heart rates (compliance) was assessed |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in insulin sensitivity | change in baseline insulin sensitivity at 6 weeks | insulin dose was recorded pre and post training by participants |
| change in glycaemic control | change in baseline glycaemic control at 6 weeks | participants recorded their blood glucose concentrations in the first and final weeks of the intervention |
Countries
United Kingdom
Outcome results
None listed