Metabolic Disease, Obesity, Exercise
Conditions
Brief summary
The purpose of this study is to assess the effects of acute beetroot juice supplementation on exercise performance and cardiometabolic health in obese individuals with secondary cardiometabolic complications. Additionally, we will determine if the ergogenic health benefits of beetroot juice is due to the nitric oxide compound within the product, the antioxidant compound within the product, or a combination of the two compounds.
Interventions
DIETARY_SUPPLEMENTSodium Nitrate
70ml sodium nitrate, matched for nitrate concentration in Beetroot Juice arm
DIETARY_SUPPLEMENTBeetroot Juice no Nitrate
70ml Concentrated Beetroot Juice with nitrate removed
DIETARY_SUPPLEMENTBeetroot Juice
70ml Concentrated Beetroot Juice
Sponsors
University of Alabama at Birmingham
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* BMI ≥ 30 kg/m2 * Able to perform exercise testing on a cycle ergometer
Exclusion criteria
* Currently taking medications know to affect cardiovascular or respiratory function * Currently supplementing with an antioxidant compound * Current smoker * Currently taking antibiotics * Not willing to abstain from mouthwash use * Currently participating in regular physical activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to Exhaustion | A Time to Exhaustion Test will be conducted on each participant a total of four times throughout their participation in the study. This will take place approximately 2.5 hours post ingestion of the dietary supplement they are randomized to at each visit. |
Countries
United States
Outcome results
None listed