Type1diabetes
Conditions
Brief summary
This study aims to compare the effect of a bout of high-intensity interval training (HIT) with a bout of moderate-intensity continuous training (MICT) on glucose concentrations over the subsequent 24h period.
Detailed description
This study aims to compare the effect of a bout of high-intensity interval training (HIT) with a bout of moderate-intensity continuous training (MICT) on glucose concentrations over the subsequent 24h period. Fourteen people with type 1 diabetes (duration of type 1 diabetes 8.2±1.4 years), all on basal-bolus regimen, completed a randomised, counterbalanced, crossover study. Continuous glucose monitoring was used to assess glycaemic control following a single bout of HIT (6 x 1min intervals) and 30 mins of moderate-intensity continuous training (MICT) on separate days, compared to a non-exercise control day (CON). Exercise was undertaken following an overnight fast with omission of short-acting insulin. Capillary blood glucose samples were recorded pre and post-exercise to assess the acute changes in glycaemia during HIT and MICT.
Interventions
BEHAVIORALEffects of the type of exercise on blood glucose concentrations
glucose concentrations were assessed over the 24 hour periods following no exercise, a single bout of high intensity interval training and a single bout of moderate intensity continuous training
Sponsors
Liverpool John Moores University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* duration of type 1 diabetes \>6 months * basal bolus regimen * no significant history of hyper- or hypoglycaemia (determined from medical history
Exclusion criteria
* duration of type 1 diabetes \<6 months, * insulin pump therapy * significant history of hyper- or hypoglycaemia (determined from medical history) * obesity (BMI \>30 kg∙m-2) * pregnancy or planning pregnancy, uncontrolled hypertension (\>180/100 mmHg) * angina * autonomic neuropathy * taking any medication that affects heart rate * major surgery planned within 6 weeks of the study * severe nonproliferative and * unstable proliferative retinopathy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| 24 hour glycaemic profile | 24 hours | Continuous glucose monitoring will be used to assess the effects of an acute bout of fasted high intensity interval training or moderate intensity continuous training on 24 hour glycaemic profile. |
Countries
United Kingdom
Outcome results
None listed