The Relationship Between Nocturnal Enuresis And Spina Bifida Occulta

The Relationship Between Nocturnal Enuresis And Spina Bifida Occulta: A Prospective Controlled Trial

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03543995

Enrollment

330

Registered

2018-06-01

Start date

2017-01-01

Completion date

2018-05-15

Last updated

2018-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enuresis, Nocturnal, Spina Bifida

Keywords

lower urinary tract symptoms, nocturnal enuresis, spina bifida occulta, treatment response

Brief summary

It is claimed that SBO may be responsible for bladder dysfunction in patients without known neurological disease. Subsequently, it was reported that the frequency of SBO in NE cases was higher than normal children. However, in controlled trials, SBO frequency was not different in NE patients compared to the normal population. Conversely, the incidence of dysfunctional bladder in the presence of SBO in NE patients was found to be higher and the response to treatment was worse than in non-SBO patients. The present study aimed to determine whether the frequency of SBO in patients with NE was higher than in healthy subjects, the effect of SBO on the severity of LUTS and whether treatment response of primary NE patients changed in the presence of SBO.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Years to 15 Years

Healthy volunteers

Inclusion criteria

* Patients aged 6 to 15 years * at least one night-time wetting weekly

Exclusion criteria

* neurological disease, * diabetes mellitus or insipidus, * spinal surgery history, spina bifida skin findings, * chronic renal insufficiency * and secondary enuresis

Design outcomes

Primary

Measure	Time frame	Description
Dry bed days	3 months	Patients were called for check-up one and three months later. When waking in the morning they were given a form to mark as dry or wet, and dry bed days were examined at check-up.

Outcome results