Evaluation of the Value of Cerebral Perfusion Scintigraphy in the Study of Post-stroke Fatigability

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03543280

Enrollment

Registered

2018-06-01

Start date

2018-02-23

Completion date

2019-02-28

Last updated

2018-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fatigability Post Stroke

Keywords

fatigability post stroke, post stroke, high-speed CT, MRI

Brief summary

At present there is no consensus for post-stroke imaging except for the realization of early cerebral CT at 24 hours post-thrombolysis. The use of cerebral perfusion scintigraphy would predict the course of a stroke. Indeed, it has been shown that a good perfusion is linked to a good evolution of the neurological deficit. This test is used routinely to evaluate cerebral perfusion in patients with stroke. This technique was also used to study the mechanisms of post-stroke aphasia and to highlight neuronal disconnections after stroke, a reflection of the functioning of neural networks. Neuropsychological tests are almost always done at 3 months. Fatigue is studied: PSF scale at 3 months, 6 months and 2 years. Research needs to be continued in this area because the pathophysiology remains unknown and the symptoms are disabling for patients. Using cerebral perfusion imaging would bring elements of understanding of this mechanism and ultimately improve the management of patients.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Inclusion criteria

* Patients: 18 to 60 years old at the initial diagnosis * Admission for transient ischemic attack, stroke, dissection, TVC * RANKIN less than or equal to 2 * Neuropsychological tests at +3 months: MoCA\> 26 (to eliminate cognitive deteriorations too important for the good realization of the battery) * Absence of psychiatric history * Absence of psychotropic medication * No history of stroke * No complaint of pre-stroke fatigue * Having signed the consent form

Exclusion criteria

* Impossibility of giving the subject or his family enlightened information (subject in emergency situation, difficulties in understanding the subject, etc.) * Subject under the protection of justice * Subject under guardianship or curatorship * Refusal of the patient to participate in the study

Design outcomes

Primary

Measure	Time frame
Evaluate fatigue symptoms in stroke patients	After the period following a stroke: 1 month

Countries

France

Contacts

Primary ContactIzzie Jacques NAMER, MD, PhD

Izzie.Jacques.NAMER@chru-strasbourg.fr33 3 88 12 75 50

Outcome results