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Hypoalgesic Effect of Cervical Manipulation

Hypoalgesic Effects of Specific vs Non-specific Cervical Manipulation in Healthy Subjects

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03541538
Enrollment
21
Registered
2018-05-30
Start date
2018-06-20
Completion date
2018-07-20
Last updated
2020-07-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Keywords

joint manipulation, cervical, pressure pain, manual therapy

Brief summary

This study evaluates the hypoalgesic effect of global and specific cervical joint manipulation in healthy individuals. At first the participants received one of the interventions and after 48 hours, the other.

Detailed description

Cervical Joint Manipulation (CJM) are often used for pain treatment. Joint manipulation generates a series of stimuli within the central nervous system through the activation of proprioceptors located in the joint capsule or muscles, stimulates the PAG, causing pain inhibition by activation of non-opioid descending inhibitory pathways.

Interventions

DEVICEGlobal manipulation

The therapist positioned himself at the head of the stretcher and with one hand supported the side of the participant's face. With the other hand supported the opposite face of the same and then performed contralateral rotation of the cervical and a slight traction to the tissue barrier to perform the manipulation impulse of high speed and short amplitude in rotation. The procedure was carried out bilaterally.

DEVICEEspecific manipulation

The therapist positioned himself at the head of the stretcher and with one hand kept the middle phalange of the second finger laterally on the articular processes of the C6-7 vertebrae. With the contralateral hand he supported the opposing face of the participant by performing a tilt up to the C6-7 segment and contralateral rotation up to the tissue barrier to carry out the impulse quickly and short. The procedure was carried out bilaterally.

Sponsors

Universidade Federal de Sao Carlos
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Outcomes Assessor)

Masking description

Examiner 1 will receive the blinding outcome will be asked: Which intervention does the patienth as received: global manipulation or especific manipulation Their responses to these questions will be recorded and used to measure the adequacy of participants and examiners.

Intervention model description

Participants received two interventions randomly at two times: global manipulation (GM) and specific manipulation (MS)

Eligibility

Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* healthy subjects of both sexes * without pain complaints in the last 90 days

Exclusion criteria

* previous spinal surgeries * spinal canal stenosis * vertebral fracture * spondylolisthesis * cancer * acute infections * hemorrhagic disorders * active tuberculosis * deep vein thrombosis * osteoporosis * rheumatic diseases * metabolic diseases * cardiorespiratory diseases * smoking injury * musculoskeletal injury * use of pacemaker * women in menstrual period * pregnant women * use of pain-killers in the last 48 hours * use of anti-inflammatory drugs in the last 48 hours * previous joint manipulation treatments * aversion to cervical joint manipulation * positivity in the vertebral artery test * headache in the last seven days

Design outcomes

Primary

MeasureTime frameDescription
Pressure Pain Threshold at the posterior region of the forearm1 minute after the end of the intervention.The subjects were placed supine on a stretcher with their elbows fully extended and the anterior portion of the forearm resting on the stretcher. Subjects were instructed to keep their eyes closed during attempts. The examiner used a Somedic Type II digital pressure algometer (Somedic Inc, Hörby, Sweden) on the posterior region of the forearm 10cm below the lateral epicondyle of the elbow towards the third finger, keeping the forearm in pronation. The pressure was then applied perpendicular to the skin at a rate of 40kPa / s using a 1cm2 flat circular probe covered with 1mm of rubber to prevent any skin pain caused by sharp metal edges.

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026