Congenital Heart Disease
Conditions
Brief summary
We will test an ultrasound device that uses sound waves to detect the fetal heart beat, and use this device to tell the MRI scanner when to collect pictures of the fetal heart. This will help freeze motion of the fetal heart, to make MRI pictures sharper. This will be important for assessing human fetal heart disease, an active area of research at our institution.
Interventions
DEVICESMART-SYNC LM03
Doppler ultrasound cardiac gating device for fetal MRI application
Sponsors
The Hospital for Sick Children
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DEVICE_FEASIBILITY
Masking
NONE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* pregnant adults (age 18 and up) with fetus affected by congenital heart disease * singleton pregnancy in their 2nd and 3rd trimesters * scheduled for a clinical fetal ultrasound examination at the Fetal Echocardiography Clinic at SickKids
Exclusion criteria
* claustrophobia * cardiac pacemaker * non-MRI compatible implants * non-singleton pregnancy * obesity (BMI \> 30)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Comparison between fetal MRI and fetal echocardiography | within 2 weeks of participation in the study | Anatomic MR images of the fetal heart will be acquired using prospective gating information from the Doppler ultrasound probe (SMART-SYNC LM03) and used to calculate ejection fraction. These values will be compared with corresponding reference values obtained during the patient's visit to the Fetal Echocardiography Clinic. |
Countries
Canada
Outcome results
None listed