Cognitive Dysfunction, Physical Disability
Conditions
Keywords
Cardiovascular health, Diet, Functional limitations, Frailty, Older Adults
Brief summary
Population aging makes it necessary to identify factors related to unhealthy aging. The purpose of this study is to examine the association between ideal cardiovascular health, diet and other lifestyles and biological risk factors (either clasical or emergent) and the risk of physical and cognitive function impairment and mortality in a cohort of community-living individuals aged 65 years and over.
Interventions
None listed
Sponsors
Universidad Autonoma de Madrid
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to 95 Years
Healthy volunteers
No
Inclusion criteria
* Non-institutionalized residents in the region of Madrid, Spain. * 65 years and over
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Functional limitations on taste function | 3 years | NIH Tool Box Taste test |
| Functional limitations on auditory function | 3 years | Audiometry |
| Functional limitations on bicep-femoral flexibility | 3 years | Chair Sit and Reach test |
| Functional limitations on shoulder flexibility | 3 years | Back Scratch test |
| Functional limitations on balance | 3 years | Short Physical Performance Battery (SPPB): Balance test |
| Functional limitations on gait speed | 3 years | Short Physical Performance Battery (SPPB): Gait Speed test |
| Functional limitations on strength of legs | 3 years | Short Physical Performance Battery (SPPB): Chair Stand test |
| Functional limitations on strength of hands | 3 years | Hydraulic hand dynamometer (Jamar Plus +) |
| Functional limitations on activities of daily living | 3 years | Activities of Daily Living (ADLs) test |
| Functional limitations on instrumental activities of daily living | 3 years | Instrumental Activities of Daily Living (IADLs) test |
| Functional limitations on olfactory function | 3 years | Pocket Smell test |
| Cognitive impairment | 3 years | Mini-Mental State Examination (MMSE) |
| Executive function limitations on working memory | 3 years | Digits Forward test (WAIS-III), |
| Executive function limitations on programmed motor tasks | 3 years | Three Hand Position test of Luria |
| Executive function limitations on motor response control | 3 years | GO-NO-GO test. |
| Memory function limitations | 3 years | Seven Minute Screen (orientation, memory, clock drawing, verbal fluency) |
| Frailty | 3 years | Fried criteria |
| Falls | 3 years | From the question: How many times have you fallen down since the last interview? a) Number of falls; b) Number of injurious falls; c) Number of falls with fracture |
| Arterial stiffness estimated by pulse wave velocity (PWV) | 3 years | Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate PWV (m/s) over a 24 hours period |
| Arterial stiffness estimated by central sistolic blood pressure (CSBP) | 3 years | Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate CSBP (mmHg) over a 24 hours period |
| Arterial stiffness estimated by augmentation index (AI) | 3 years | Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate AI (%) over a 24 hours period |
| 24-h systolic and diastolic blood pressure | 3 years | Ambulatory Blood Pressure Monitor using the oscillometric method (Mobil-O-Graph PWA) to estimate brachial blood pressure (systolic and diastolic) (mmHg) over a 24 hours period |
| Mortality | 3 years | From the National Institute of Statistics of Spain |
Countries
Spain
Outcome results
None listed