PEEP During Induction of Anesthesia in Small Children

The Effect of Positive End-expiratory Pressure During Induction of General Anesthesia on Atelectasis Formation and Non-hypoxic Apnea Time in Small Children: a Randomized Controlled Trials

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03540940

Enrollment

Registered

2018-05-30

Start date

2018-05-21

Completion date

2019-08-14

Last updated

2019-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pediatric Anesthesia

Brief summary

Positive end-expiratory pressure (PEEP) applied during induction of anesthesia prevents atelectasis formation and increases the duration of nonhypoxic apnea in obese and nonobese patients. PEEP also prevents atelectasis formation in pediatric patients. Because pediatric patients arterial desaturation during induction of anesthesia develops rapidly, we studied the clinical benefit of PEEP applied during anesthesia induction.

Interventions

OTHERPEEP

7cmH2O positive end expiratory pressure

OTHERZEEP

0 cmH2O positive end expiratory pressure

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

1 Months to 2 Years

Healthy volunteers

Inclusion criteria

* pediatric patients undergoing general anesthesia using endotracheal intubation

Exclusion criteria

* previous history of lung disease * anticipated difficulty in airway management

Design outcomes

Primary

Measure	Time frame
Duration of Apnea	from the start of apnea until SpO2 reached 95%, maximum 5 minutes.

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 17, 2026