Myeloid-derived Suppressor Cells in Sepsis

The Roles of MDSCs (Myeloid-derived Suppressor Cells) in Adult Patients With Sepsis.

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03540797

Enrollment

125

Registered

2018-05-30

Start date

2015-07-01

Completion date

2023-12-31

Last updated

2018-05-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Brief summary

This study is designed for septic patients, to isolate MDSCs and the correlation of prognosis of sepsis. The purpose of this study hopes to explore the phenomenon and possible mechanisms of MDSCs in patients with severe sepsis.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

* Patients must have known origin of infection . * Systemic inflammatory response syndrome.

Exclusion criteria

* age less than 18 years * pregnancy * known anaphylactoid reaction to colloid fluids * a life expectancy less than 24 hours, * inability to provide informed, written consent * Patients receiving nephrotoxic drugs, * admitted to the hospital following a surgical procedure, * sepsis more than 72 hours when screening .

Design outcomes

Primary

Measure	Time frame
Survival of Intensive care unit (ICU) stay	28 days

Secondary

Measure	Time frame
In hospital survival	90 days

Countries

Taiwan

Contacts

Primary ContactFu-Tsai Chung, MD

vikingchung@yahoo.com.tw+886-3281200

Outcome results