Quality of Life in Patients With Multiple Myeloma-validation Study

Validation of the Myeloma Patient Outcome Scale (MyPOS) Assessing the Quality of Life in Patients With Multiple Myeloma in the German Speaking Part of Switzerland

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03537222

Enrollment

Registered

2018-05-25

Start date

2018-10-10

Completion date

2021-07-31

Last updated

2021-10-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Multiple Myeloma

Keywords

quality of life, psychometrics

Brief summary

In this study, the Myeloma Patient Outcome Scale (MyPOS) will be translated from English to German. This translated version will be quantitatively and qualitatively validated with patients with multiple myeloma.

Detailed description

Patients with multiple myeloma (N=10) will be interviewed in the qualitative phase about their comprehension of the translated MyPOS. The questionnaire will be revised according to the results of the interviews. This culturally adapted Swiss-German MyPOS will be assessed in the quantitative phase for its' psychometric properties with 200 patients with multiple myeloma.

Interventions

DIAGNOSTIC_TESTMyeloma Patient Outcome Scale (MyPOS)

Patients complete the MyPOS questionnaire on quality of life

Study design

Observational model

OTHER

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Inclusion criteria

* informed consent as documented by signature * confirmed histological diagnosis of multiple myeloma, * age ≥ 18 years, * mental capacity to give written informed consent

Exclusion criteria

* inability to communicate in German * participation in another clinical study * more than one cancer diagnosis * mental illness (i.e. psychiatric diagnosis)

Design outcomes

Primary

Measure	Time frame	Description
Psychometric properties of the culturally-adapted Swiss-German Myeloma Patient Outcome Scale (MyPOS)	upon enrollment	The primary outcome will be the scores on each item of the culturally-adapted Swiss-German MyPOS. Items are scored on a five-point Likert scale. For the analysis, the three subscales Symptoms (range: 0-52), Emotions (range:0-68) and Healthcare Support (range: 0-12) are assessed as well as the MyPOS total score (range: 0-132 ) by summing up the item scores ranging from 0-4. Higher scores reflect worse quality of life. The scores will be used to evaluate the psychometric properties of the culturally-adapted Swiss-German MyPOS: * Structural validity, * Internal consistency, * Construct validity, * Convergent and divergent validity.

Countries

Switzerland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026