Dietary Assessment and Prevalence of Refeeding Syndrome in High-risk TB Patients in Chhattisgarh, India

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03537170

Enrollment

Registered

2018-05-25

Start date

2017-11-23

Completion date

2018-02-14

Last updated

2018-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Refeeding Syndrome, Severe Malnutrition, Tuberculosis

Brief summary

Severe tuberculosis (TB) leads to wasting and anorexia, increasing risk of the refeeding syndrome (RFS) as defined by current criteria. TB patients have high metabolic rates and require a high calorie diet, with nutritional supplementation programs improving outcomes. BMI inversely correlates with mortality in these patients. Risk of RFS, a life-threatening syndrome associated with initiation of feeding after a period of low intake, has not been studied in this population and it is not known whether severely malnourished TB patients benefit from lower caloric intake. This study aimed to examine the prevalence of RFS in TB inpatients in rural India and correlate this with baseline and inpatient caloric intake.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* all adult inpatients admitted to the TB ward * able to take enteral intake

Exclusion criteria

* unable to take enteral intake

Design outcomes

Primary

Measure	Time frame
Inpatient caloric intake	from date of admission to discharge, up to 100 weeks

Secondary

Measure	Time frame
Incidence of refeeding syndrome	from date of admission to discharge, up to 100 weeks

Countries

India

Outcome results