Oxygenation and Perfusion in Patients With Acute Migraine Attacks

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03536936

Acronym

OPAMA

Enrollment

1000

Registered

2018-05-25

Start date

2010-01-01

Completion date

2018-04-30

Last updated

2018-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Migraine, Migraine; Status, Migraine With Aura

Brief summary

The aim of the study is to retrospectively evaluate brain perfusion and oxygenation in acute migraine attacks. Magnetic resonance perfusion and susceptibility weighted imaging are the technics to measure perfusion and oxygenation respectively.

Detailed description

The aim of the study is to demonstrate a possible correlation between areas of hypoperfusion and prominent cortical veins during migraine attacks. These focal ares of altered vascular supply of the brain will be evaluated for correlation with topograhy of symptoms.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Years to 80 Years

Inclusion criteria

final clinical diagnosis of migraine

Exclusion criteria

brain tumors, seizures/epilepsy, confirmed cerebral infarct from cerebral atery occlusion, sinus vein thrombosis;

Design outcomes

Primary

Measure	Time frame	Description
Focal cerebral hypoperfusion and elevated oxygenation in acute migraine attack	Patients, who are admitted to hospital, undergo magnetic resonance imaging within 5 days of migraine attack; time frame: symptoms to imaging : 5 days;	Focal cerebral hypoperfusion and elevated oxygenation in acute migraine attack, measured with visual scores on imaging, using a consensus between two readers

Outcome results