Role of TAP and RS Block in Reduction of Postoperative Pain for Gynecological Surgical Laparoscopic Procedures

The Role of Transversus Abdominis Plane Block and Rectus Sheath Block in Reduction of Postoperative Pain for Gynecological Benign Surgical Laparoscopic Procedures: a Randomized Controlled Trial

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03536741

Enrollment

Registered

2018-05-25

Start date

2017-10-12

Completion date

2018-07-12

Last updated

2018-05-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

TAP and RS Block

Brief summary

The present study aims to demonstrate the effectiveness of loco-regional wall anesthesia of the transversus abdominis plane block (TAP block) and the rectus sheath block (RS block), compared to intravenous analgesia, in terms of pain reduction, postoperative analgesic drugs consumption, patient satisfaction and decrease of LOS (length of stay), in patients undergoing benign gynecological laparoscopic surgical procedures.

Interventions

PROCEDURETAP block and RS block + General Intravenous Anesthestic

transversus abdominis plane block and rectus sheath block

DRUGGeneral Intravenous Anesthetic

General Intravenous Anesthetic

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

FEMALE

Age

18 Years to 75 Years

Healthy volunteers

Inclusion criteria

* patients undergoing benign laparoscopic gynecological surgery * age between 18 and 75 years * BMI \>18 e \<35 * ECOG Performance Status 0-1

Exclusion criteria

* age \< 18 or \> 75 years * BMI \<18 or \> 35 * ECOG Performance Status \>1 * Allergy to local anesthetics * Allergy to NSAIDs * Chronic kidney failure \> II class * Systemic neoplastic disease actual or previous * Actual pregnancy * Active or recent pelvic inflammation * Persistent coagulopathy * Previous opioids consumption for chronic pain * Neurological or cognitive disorders * Conversion from laparoscopic to open surgery * Onset of intraoperative complications

Design outcomes

Primary

Measure	Time frame	Description
postoperative pain in the first 72 hours after gynecological surgical procedures	postoperative pain in the first 72 hours after gynecological surgical procedures	postoperative pain in the first 72 hours after gynecological surgical procedures
analgesic consumption in the first 72 hours after gynecological surgical procedures	analgesic consumption in the first 72 hours after gynecological surgical procedures	analgesic consumption in the first 72 hours after gynecological surgical procedures

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026