Nonalcoholic Fatty Liver Disease and Cardiovascular Disease: the Correlation Analysis and Risk Prediction Model Study

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03534908

Enrollment

5000000

Registered

2018-05-23

Start date

2017-09-25

Completion date

2021-06-30

Last updated

2019-10-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular Diseases, NAFLD

Brief summary

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the world. NAFLD is associated with a lot of comorbidity, such as diabetes, metabolic syndrome, coronary heart disease and chronic kidney diseases. However, the correlation between the NAFLD and cardiovascular disease (CVD) events remains controversial. This study is an observational study based on a big retrospective cohort in china to explore the prevalence of NAFLD in China, the risk factors associated with NAFLD, as well as whether patients with NAFLD are more prone to experience CVDs and CVD events.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 75 Years

Healthy volunteers

Yes

Inclusion criteria

* males or females aged 18-75

Exclusion criteria

* malignancy except primary liver cancer * pregnancy or breastfeeding * liver diseases of other etiology including hepatitis C virus infection ,autoimmune hepatitis,Wilson's disease,hemachromatosis,drug-induced hepatitis,parenteral nutrition * excessive alcohol consumption * cases missing crucial data

Design outcomes

Primary

Measure	Time frame
the prevalence of NAFLD in China	June，2020

Secondary

Measure	Time frame
the risk factors associated with NAFLD	August，2020
to indicate the prevalence of CVDs and CVD events in people with and without NAFLD	October，2020

Countries

China

Outcome results