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Development and Pathological Changes of High Myopia Among Children and Adolescents in China

A Longitudinal Study on the Development and Pathological Changes Among Children and Adolescents With High Myopia in China

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03533647
Enrollment
1400
Registered
2018-05-23
Start date
2018-05-14
Completion date
2021-05-31
Last updated
2018-06-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

High Myopia

Keywords

high myopia, ocular biometric parameters, adolescent, children

Brief summary

The study aims to observe the relationship between the changes of ocular structure parameters and pathological changes among children and adolescents with high myopia. Environmental factors and family history will also be collected to explore their impacts on high myopia progression.

Detailed description

This study aims to observe children and adolescents with high myopia for 3 years, and to collect data of ocular pathological changes, family history and environmental factors so as to understand the natural course and internal laws of the development of high myopia.

Interventions

OTHERObservational

none (observational study)

Sponsors

Zhongshan Ophthalmic Center, Sun Yat-sen University
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
Yes

Inclusion criteria

* 9 to 18 years old school students in Guangzhou, with either eye had myopia equal or greater than 6.0D * Or 6 to 8 years old school students in Guangzhou, with either eye had myopia equal or greater than 3.0D * Written informed consent for study participation * Be willing to cooperate with the relevant ophthalmological examination and complete the questionnaire.

Exclusion criteria

* None school students in Guangzhou * Other contraindications * A history of allergy to tropicamide or topical anesthetics * Missing ability to give informed consent

Design outcomes

Primary

MeasureTime frameDescription
To observe the relationship between the changes of ocular structure parameters and pathological changes among children with high myopia.examine every 12 months, follow up 3 yearsexamine the ocular pathological changes

Secondary

MeasureTime frameDescription
To explore the impact of environmental factors and genetic factors on the progression among children and adolescents with high myopiaexamine every 12 months, follow up 3 yearsaxial length, refractive error changes, environmental factors, family history, exercise time, eye care habits, form of exercise

Countries

China

Contacts

Primary ContactYuting LI, master
ytdorothy@163.com+86-020-87334687
Backup ContactQianyun CHEN, Bachelor
torunchen@163.com+86-020-87334687

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026