Heart Injuries, Hip Fractures, Hypotension, Renal Insufficiency
Conditions
Brief summary
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as well as renal failure noted by Changes in Serum Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP
Detailed description
Patients with acute hip fractures are old and vulnerable. With a majoriry classified as being ASA 3 or more. Frequently they receive spinal anesthesia perioperatively inducing hypotension. Even a short hypotensive period may induce postop cardiac T roponinT leakage as awell as renal failure noted by Changes in S Creatinin or Cýstatin C This will be investigated and correlated to intraoperative hypotension as a step one. Preliminary this will be followed by an intervention with vasopressor treatment perioperatively to preserve an adequte MABP
Interventions
DIAGNOSTIC_TESTSerum Tropinin
Blodsamples will be taken 4 times from preoperatively to 2 Days postoperatively
Sponsors
Sahlgrenska University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Hip fracture patient to be operated upon Classified as being ASA 3 or more
Exclusion criteria
* Not forfilling inclusion Criterias
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mortality | 90 days | post surgery |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Serum concentrations of Troponin, NTproBNP, Creatinin and Cystatin C | 90 days | Relations between values and mortality at 30 and 90 days |
Countries
Sweden
Outcome results
None listed