Uveitis
Conditions
Brief summary
The purpose of this study is to develop and demonstrate new technologies that will enable a non-contact, compact eye imaging system based on OCT to assist an early responder in acute care settings (like an emergency room) to help assess eye trauma and inflammation (swelling inside the eye).
Interventions
DEVICEhand-held swept source optical coherence tomography
images the eye
Sponsors
Duke University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DEVICE_FEASIBILITY
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
\- Pre-clinical: employees or students (over the age of 18) of the Duke Eye Center or Biomedical Engineering willing to be imaged with OCT system \- Pilot (ER): patients (over the age of 18) presenting emergently to the Duke Emergency room with traumatic eye injuries and/or suspected open globe \- Pilot (Uveitis): patients presenting to the Duke Eye Center with active uveitis and microhyphema or hyphema; patients who have independently consented to undergo vitreous tap or biopsy for their uveitis care at the Duke Eye Center
Exclusion criteria
\- Pre-clinical: subject cannot be a direct report to any of the PIs or other key personnel of this study \- Pilot (ER): hemodynamically unstable, unable to consent \- Pilot (Uveitis): unable to consent; cornea or lens opacity/scar which would block the imaging modality
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Concordance | Up to 18 months | By the ability to detect cells in the eye compared to clinical exam |
Countries
United States
Outcome results
None listed