Lidocaine Reduces Muscle Tremor is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring

Lidocaine Reduces Muscle Tremor Caused by Electric Energy Devices, Which is Beneficial for Intraoperative Recurrent Laryngeal Nerve Monitoring During Endoscopic Thyroid Lateral Neck Dissection

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03530033

Enrollment

Registered

2018-05-21

Start date

2018-05-01

Completion date

2018-10-31

Last updated

2018-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Accessory Nerve Injuries, EMG: Repetitive Nerve Stimulation Abnormality, Neck Cancer, Recurrent Laryngeal Nerve Injuries, Thyroid Cancer

Brief summary

In recent years, the application of intraoperative recurrent laryngeal nerve monitoring in thyroid surgery has greatly reduced the complications of recurrent laryngeal nerve injury. The use of intraoperative neurological monitoring requires the reduction of the dose of neuromuscular blockade, which often leads to muscle tremors during the application of electrical energy, which affects the fine separation around the muscles. This study explored the effect of local application of lidocaine on reducing muscle tremor during surgery and its optimal dose.

Detailed description

According to the random number method, eligible patients were randomly divided into 2 groups. Group A was the conventional surgery group, and Group B was the lidocaine group. The operative time for the separation of the sternocleidomastoid muscle from the two groups of patients was analyzed, as well as the length of time for the search for the accessory nerve and the effect of intraoperative nerve monitoring on the EMG signal.

Interventions

DRUGLidocaine

Local injection of lidocaine reduces muscle tremor

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Thyroid papillary carcinoma * Lateral cervical lymph node metastasis * The diameter of the metastatic lymph nodes is less than 3cm * Without internal jugular vein invasion

Exclusion criteria

* Lidocaine allergy sufferers

Design outcomes

Primary

Measure	Time frame	Description
dose of lidocaine	At the end of surgery	dose of lidocaine
Number of nerve signal loss cases	At the end of surgery	Number of nerve signal loss cases
Anatomical time of accessory nerve	At the end of surgery	Anatomical time of accessory nerve
dose of muscle relaxant drugs	At the end of surgery	dose of muscle relaxant drugs
The satisfaction of sternocleidomastoid muscle separation	At the end of surgery	The visual score was 5 points for the most satisfaction and 0 points for the most dissatisfied.

Countries

China

Contacts

Primary Contactbo wang, md

wangbo@fjmu.edu.cn13705947900

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026