Reactivation of Hepatitis B Virus
Conditions
Keywords
Leukemia, occult hepatitis B virus infection
Brief summary
Children with clinically diagnosed leukemia may experience occult HBV infection after chemotherapy immunosuppressive therapy, which may affect the normal course of leukemia treatment. However, this is not caused by clinically relevant diagnosis and treatment measures but exists in vivo.
Detailed description
The clinical diagnosis of children with leukemia may be due to the influence of leukemia disease on the immune cells of the children and the damage to the immune system due to immunosuppressive therapy in children. Therefore, the risk of contracting hepatitis B virus is relatively high, and some children are In the treatment of immunosuppressive chemotherapy (later), the reactivation of occult HBV infection has an impact on the normal course of leukemia treatment. However, this is not a clinically relevant diagnosis and treatment measure. It is necessary to avoid unnecessary conflicts between clinical doctors and patients as much as possible.
Interventions
None listed
Sponsors
Children's Hospital of Chongqing Medical University
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
1 Years to 16 Years
Healthy volunteers
Yes
Inclusion criteria
The clinical diagnosis of children with leukemia received systemic chemotherapy.
Exclusion criteria
Children with non-leukemia and children without appropriate treatment.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| HBV-DNA positive | 1-year | Positive HBV nucleic acid test |
Countries
China
Contacts
Primary ContactYao Zhao
Outcome results
None listed