Peripheral Vascular Disease in Diabetes
Conditions
Keywords
Diabetes, Peripheral Vascular Disease, Microcirculation
Brief summary
The main aim of the present study was to evaluate the microcirculation of peripheral vascular disease in diabetes.
Interventions
DIAGNOSTIC_TESTFive points test of Tongji university
In each group, we will evaluate the microcirculation of diabetic foot using the newly-established Five points test of Tongji university before or after the operation, and then compare the temperature of the five points with the other data.
Sponsors
Shanghai 10th People's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* 1.Patients with Peripheral vascular disease with or without diabetes. 2.Rutherford class 2-6. 3.Target lesions with a diameter reduction of at least 50% on angiography, and without past history of any intervention. 4.Target vessel with 2.0--10.0mm in diameter and having a lesion of about 4cm-20cm in length. 5.Written informed consent signed by the patients or representatives
Exclusion criteria
* 1.Previous bypass surgery or stent placement at the ipsilateral lower limb 2.History of intolerance to antiplatelet therapy, heparin, or contrast media. 3.Bleeding diathesis; 4.Active systemic bacterial infection; 5.Severely impaired renal function (serum creatinine level \> 2.5 mg/dL. Expected survival time of less than 24 months
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Coincidence rate of 5 points test of Tongji university | 12 months | The primary study endpoint was that the coincidence rate of evaluating the microcirculation by the newly-established 5 points test of Tongji university attains over 95% before and after operations as assessed by digital substraction angiography (DSA). |
Countries
China
Contacts
Primary ContactMaoquan Li, Ph.D
Outcome results
None listed