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Effect of Laparoscopic Ovarian Drilling on Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome

Effect of Laparoscopic Ovarian Drilling on the Outcomes of in Vitro Fertilisation in Clomiphene-resistant Women With Polycystic Ovary Syndrome

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03527979
Enrollment
88
Registered
2018-05-17
Start date
2018-03-01
Completion date
2018-09-30
Last updated
2018-05-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

PCOS

Brief summary

the polycystic ovarian syndrome is associated with an ovulation and infertility. recently the laparoscopic ovarian drilling has been used as surgical treatment for ovulation in women with polycystic ovarian syndrome, although its mechanism and outcomes are still unclear. this study is undertaken to evaluate the in vitro fertilisation outcomes in clomiphene-resistant women with PCOS who were treated with LOD.

Interventions

PROCEDUREIVF/ICSI

IVF/ICSI

Sponsors

Ain Shams University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
FEMALE
Age
25 Years to 35 Years
Healthy volunteers
No

Inclusion criteria

* age between 25 and 35 * patients with established PCOS * history at least one year infertility * no response to clomiphene citrate for at least three cycles

Exclusion criteria

* history of previous IVF/ICSI * chronic disease such as thyroid disorder and DM * infertility due to sever male factor * sever endometriosis * infertility due to uterine factor such as multiple fibroid * body mass index \> 30

Design outcomes

Primary

MeasureTime frameDescription
clinical pregnancy rate confirmed by b-hcg and visualizations of gestational sac by ultrasound3 monthsPregnancy confirmed by b-hcg and visualization of gestational sac by ultrasound

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026