Periodontal Diseases
Conditions
Keywords
aggressive periodontitis, healthy peri-implant, chairside test, chronic periodontitis
Brief summary
The aim of this study to evaluate the diagnostic accuracy of a new qualitative aMMP-8 POC test in different periodontal health and disease and as compared to the established quantitative laboratory method (ELISA)
Detailed description
MMP-8 has been reported to reflect the inflammatory status in periodontal tissues and, therefore represent as potential biomarkers of periodontitis. A positive aMMP-8 test could be an early indicator of these excessive and undesired tissue reactions.
Interventions
DIAGNOSTIC_TESTGCF collection with aMMP-8 chair side test
OTHERSaliva collection
Sponsors
Aydin Adnan Menderes University
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Inclusion criteria
* Systemically healthy * Nonsmokers
Exclusion criteria
* Participants were not included if they had systemic disease such as diabetes, cardiovascular. * Participants who took regular medications that could affect of periodontal tissue * Participants who received antibiotics less than 10 weeks before the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| aMMP-8 levels of GCF | 2 hours | GCF levels measured by IFMA |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Salivary MMP-8 levels | 2 hours | Saliva levels measured by IFMA |
Outcome results
None listed