Tic Disorders, Tourette Syndrome
Conditions
Keywords
Tic Disorders, Mindfulness, Meditation, Online, Internet-based, Treatment
Brief summary
Tourette Syndrome (TS) and Persistent Tic Disorder (PTD) are chronic and potentially disabling neurobiological conditions. Although a range of pharmacological and psychosocial treatments exists, a significant number of individuals either do not respond to the current treatments, find them unacceptable, or cannot access them. Thus, it is essential that researchers continue to pursue novel treatment approaches that can also be easily disseminated to those in need. Initial pilot data suggest that a mindfulness-based intervention may be beneficial for adults with tic disorders. In the present study, the researchers aim to further develop this mindfulness-based intervention, adapt it to be delivered online and pilot test the intervention with a small group of participants. The data from this pilot test will inform a subsequent randomized controlled trial comparing online mindfulness-based tic reduction to online psychoeducation, relaxation, and supportive therapy. The specific aim is to determine the feasibility and acceptability of Online Mindfulness-based Tic Reduction in 6 adults with TS or PTD. The researchers hypothesize that Online Mindfulness-based Tic Reduction will be feasible and acceptable to adults with tic disorders as measured by participant satisfaction, qualitative participant feedback, home practice compliance, dropout, and adverse events.
Interventions
BEHAVIORALOnline Mindfulness-based Tic Reduction
8-week online group mindfulness-based intervention for tics
Sponsors
Massachusetts General Hospital
Bowdoin College
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. 18 years of age or older, 2. possess a primary diagnosis of Tourette Syndrome or Persistent Tic Disorder, 3. fluent in English 4. residing in the United States, 5. either not be taking any tic suppressant medication or other psychotropic medication or be at a stable dose for 8 weeks prior to the baseline assessment and throughout the study
Exclusion criteria
1. be receiving concurrent psychotherapy for the duration of the study 2. have prior extensive experience with mindfulness and/or meditation and 3. cannot have another medical or psychological condition that would prevent the individual from fully engaging in the study or require a higher level of care (e.g., suicidality).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient Satisfaction Questionnaire | week 9 |
Secondary
| Measure | Time frame |
|---|---|
| Attrition Form | Weeks 1-8 |
| Adverse Events Monitoring Form | Weeks 1-9 |
| Yale Global Tic Severity Scale (YGTSS) | Week 0, Week 9 |
| Homework Compliance Questionnaire | Weeks 1-8 |
| Clinical Global Impressions Scale-Severity | Week 0, Week 9 |
| Clinical Global Impressions Scale-Improvement | Week 9 |
| Adult Tic Questionnaire | Weeks 0-9 |
Other
| Measure | Time frame |
|---|---|
| Yale-Brown Obsessive Compulsive Scale | Week 0, Week 9 |
| Brief Irritability Test | Week 0, Week 9 |
| Attention Deficit Hyperactivity Disorder Rating Scale | Week 0, Week 9 |
| Patient Health Questionnaire-9 | Week 0, Week 9 |
| Work and Social Adjustment Survey | Week 0, Week 9 |
| Five Facet Mindfulness Questionnaire | Weeks 0-9 |
| Credibility and Expectancy Questionnaire | Week 3 |
| Self Compassion Scale | Week 0, Week 9 |
| Affective Reactivity Index | Week 0, Week 9 |
Countries
United States
Outcome results
None listed