Chronic Kidney Disease Stage 5, Periodontal Disease
Conditions
Keywords
Glomerular filtration rate, Periodontitis, Chronic kidney disease
Brief summary
This study will evaluate periodontal and systemic parameters of a cohort of chronic kidney disease (stage 5) patients, before and three months after non-surgical periodontal treatment. It does not consider a control group.
Detailed description
Dental biofilm is a source of inflammation and infection of periodontal tissues. In the last 20 years the interaction between periodontal infections and systemic conditions has been largely studied, suggesting that the inflammation caused in the periodontal tissues could cause a response in other parts of the body. Recent studies suggest that there could be an association between periodontal disease and chronic kidney disease.
Interventions
PROCEDURENon Surgical Periodontal Therapy
Non Surgical Periodontal Therapy in 2 to 3 sessions
Sponsors
Pontificia Universidad Catolica de Chile
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Chronic kidney disease patients in Stage 5 (candidates to renal transplant)
Exclusion criteria
* Younger than 18 year old.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Clinical Attachment Level (CAL) | 3 months | Change from baseline CAL (in mm) at three months |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Bleeding on probing (BOP) | 3 months | Change from baseline BOP (%) at three months |
Countries
Chile
Contacts
Primary ContactMaite C Souyet, MsC
Backup ContactPatricio F Smith, PhD
Outcome results
None listed