Body Weight Changes, Overweight and Obesity, Physical Activity
Conditions
Brief summary
Body-weight based interval training (IT) performed 3 times per week will lead to reductions in abdominal adiposity and reduce overall body fat percentage in overweight and obese sedentary adults more effectively than moderate intensity continuous training (MICT). Body-weight interval training will improve exercise capacity (peak VO2) in overweight/obese adults.
Detailed description
Participants will be randomly assigned to one of the two home-based exercise groups. The MICT group is the standard care group and will be instructed to walk for 30 minutes, 5 days per week at a moderate intensity. The goal is to accumulate 150 minutes of continuous aerobic exercise each week. Participants will be instructed on the use of the Rating of Perceived Exertion (RPE) scale during baseline testing and will be instructed to reach an RPE of 12-16. A heart rate monitor will be worn to monitor exercise intensity. Heart rate should reach \ 70% of maximal heart rate. The IT group will perform 5 body-weight exercises in three progressive phases. During the first 2 weeks the circuit will be completed twice, 30 second intervals, 90 seconds of rest. The exercises will be performed on 3 days of the week with at least one day of rest between exercise days (ideally Monday, Wednesday, Friday). The number of repetitions will increase to a maximum of 4 while the interval and rest periods increase to a maximum of 45 seconds each. The total time spent performing intervals by week 8 will be 15 minutes. A 2 minute warm up and 3 minute cool down will be performed, such as jumping jacks or simply walking. A heart rate monitor will be used to measure exercise intensity. Heart rate should reach approximately 90% of heart rate max during the intervals. Participants will be instructed on the use of the Rating of Perceived Exertion scale during baseline testing and will be instructed to reach an RPE of ≥17 during the high intensity intervals.
Interventions
BEHAVIORALInterval Training
Interval training is prescribed 3 days per week using 5 body weight exercises in a progressive fashion.
BEHAVIORALStandard of Care
Walking prescribed to meet current exercise guidelines; 150 minutes per week.
Sponsors
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Adults 18-65 years of age * Willing and able to provide informed consent * Sedentary, overweight and obese adults (\<90 minutes of moderate intensity exercise) * BMI 25≤35 * Able to safely begin an exercise program * Have a smartphone, and willing and able to download and use the Fitbit app
Exclusion criteria
* Unable to provide informed consent. * Known cardiovascular disease, or uncontrolled hypertension, * Diagnosed type 1 or 2 diabetes * Women who are pregnant or plan to become pregnant in the next 3-4 months * Orthopedic injury/limitation or any other contraindications to exercise. * Medications that cause weight gain (steroids, HIV-related medications, etc.), or glucose lowering medications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Body fat percent | 12 weeks | DEXA derived body fat % |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in Weight | 12 weeks | Weight in kilograms |
| Change in peak VO2 | 12 weeks | Peak VO2 in ml/kg/min |
| Visceral adipose tissue area | 12 weeks | cm\^2 |
| Thigh adipose tissue area | 12 weeks | cm\^2 |
Countries
United States
Outcome results
None listed