Crohn's Disease, Upper Gastrointestinal Lesions
Conditions
Brief summary
A cross-sectional study was performed from 2017 to 2018. Consecutive Crohn's disease patients diagnosed in the Inflammatory bowel disease center of the Sixth Affiliated Hospital of Sun Yat-sen University were recruited. All patients underwent upper gastrointestinal endoscopy and biopsy by two defined endoscopists and two pathologists, the basic information were collected at the same time, in order to assess the prevalence of upper gastrointestinal involvement, and determine the role of upper gastrointestinal endoscopy in adult Crohn's disease patients, irrespective of upper gastrointestinal symptoms.
Interventions
OTHERgastroscopy
Two endoscopists performed upper gastrointestinal endoscopy and biopsy on all patients; and histological review was performed by two pathologists. From each patient, 10 specimens were taken from 6 areas in the upper gastrointestinal tract and basic informations was collected.
Sponsors
Sixth Affiliated Hospital, Sun Yat-sen University
Study design
Intervention model
SEQUENTIAL
Primary purpose
OTHER
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age is 18 years old or older * patients with diagnosis of Crohn's disease
Exclusion criteria
* diagnostic data were incomplete * patients with malignant tumor * use of PPIs or non-steroidal anti-inflammatory drugs in the preceding 4 weeks
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the incidence of different upper gastrointestinal lesions | 1 year | The incidence of different characteristic lesions of upper gastrointestinal in CD patients. |
Countries
China
Outcome results
None listed