Attention Deficit Hyperactivity Disorder
Conditions
Brief summary
The goal of this study is to create a formal, quantitative methodology to determine what is the most beneficial dose of Central Nervous System (CNS) stimulant (Ritalin, methylphenidate) to improve cognitive and behavioral function of children diagnosed with Attention Deficit Hyperactivity Disorder (ADHD) individually. If successful, it will change the way in which the dose of CNS stimulant for treating ADHD is determined for children in need of therapeutic intervention. The project will be focused on developing the necessary methodology to analyze the children's data with the drift-decision model (DDM), and to develop the required technology, i.e., a computer game with which to measure cognitive/behavioral function and its validation with eye-tracking measurements.
Interventions
OTHERno intervention. measure eye movement data
Sponsors
University of Wisconsin, Madison
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
8 Years to 12 Years
Healthy volunteers
Yes
Inclusion criteria
* 8-12 years of age; * Accompanied by caregiver (parent or legal guardian); * Able to understand and speak English; * Able to read basic English; * No counseling or current/past history of psychiatric illness, as confirmed by the Child Behavior Checklist (CBCL) and Conner's rating scale
Exclusion criteria
* Active psychosis or suicidality * History of primary psychotic disorder (e.g., schizophrenia) or bipolar disorder * Recent (past 2 weeks) substance abuse or dependence * History of brain damage or significant developmental delay * Unstable medical condition such as newly diagnosed Type I Diabetes or Rheumatoid arthritis * Use of oral steroids * Participation in the last 30 days in a clinical study involving an investigational drug * Current use of a psychotropic medicine
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Task choice | At the time of testing (the investigators are measuring acute effects, not following outcomes based on a treatment) | Subjects will perform different cognitive tasks and we will record their choices. |
| Reaction time | At the time of testing (the investigators are measuring acute effects, not following outcomes based on a treatment) | The investigators record how long it took them to make their choices. |
| Eye position | At the time of testing (the investigators are measuring acute effects, not following outcomes based on a treatment) | The tasks are eye movement based. The investigators record where the subjects were looking as voltages, which are converted to x/y coordinates through a calibration, throughout the different events of the task. |
Countries
United States
Outcome results
None listed