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Glasgow Coma Scales and General Anesthesia

The Effect of Glasgow Coma Scales on General Anesthesia in Neurosurgery Patients

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03521414
Enrollment
45
Registered
2018-05-11
Start date
2013-07-03
Completion date
2015-11-05
Last updated
2018-05-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia Awareness

Keywords

Bispectral index, Glasgow Coma Scale, intracranial pathology

Brief summary

The study evaluates the general anesthesia management with BIS monitorization in terms of hemodynamic stability, drug concentrations and drug consumption in patients who underwent surgery due to intracranial pathology and who were divided in three different GCS groups.

Detailed description

BIS monitoring is mostly used for anesthesia depth and sedation level follow-up, however it can also be used for monitoring consciousness after resuscitation of cases with acute brain injury and cardiac arrest. It is not always possible to monitor and objectively measure the changes in the level of consciousness in clinical practice. Therefore, device-based methods have been introduced in monitoring the state of consciousness. Bispectral index (BIS) monitoring may be preferred in follow up of the state of consciousness in critical patients such as those with acute brain injury, in terms of ease of use, ability to obtain numerical results and continuous monitoring. BIS monitoring is mostly used for follow up of anesthesia depth and sedation level, while it can also be applied for monitoring state of consciousness following resuscitation in cases with acute brain injury and cardiac arrest.In this study, we aimed to investigate general anesthesia management performed by bispectral index monitoring in patients who underwent surgery due to intracranial pathology and with different Glasgow Coma Scales.

Interventions

When the patients were taken to the operation table, they were monitored with the BIS. we used sevoflurane drug

DRUGSevoflurane

we used sevoflurane drug at inoperative

Sponsors

Trakya University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* 18 and 65 years * ASA II-III * intracranial surgery

Exclusion criteria

* Patients with additional disease (electrolyte impairment, uremia, etc.), * liver and renal failure affecting consciousness level other than intracranial pathology

Design outcomes

Primary

MeasureTime frameDescription
BIS, Consumption of the inhalation agents200 minutesPreoperative, intraoperative and postoperative BIS values were recorded. The total amount of opioid consumed was recorded from the infusion pump.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026