The Effect of Early Physiotherapy on Biochemical Parameters in Major Burn Patients: A Burn Center's Experience

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03520816

Enrollment

Registered

2018-05-11

Start date

2016-10-01

Completion date

2017-04-01

Last updated

2018-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns, Exercises, Physiotherapy

Keywords

Fibronectin, Prealbumin, Physiotherapy, Major Burns, biochemical parameters

Brief summary

Background: This study planned to investigate the effect of early physiotherapy on biochemical parameters in major burn patients. Methods: Ten women (50%) and 10 men (50%) aged 21-47 years old were included in our study. Participants were divided into two groups: one group was the treatment group and the other was the control group. In the treatment group, patients were admitted to the physiotherapy programme from the first day they have been hospitalised, in addition to their routine treatment (medical, surgery, etc.), for 4 days per week. It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises. The days of treatment were determined as Tuesday, Wednesday, Thursday and Friday. Patients could not be treated on a Monday because that was surgery day. The control group consisted of patients who could not receive physiotherapy due to various reasons. All patients included in the study were evaluated weekly for 6 weeks after admission to the hospital. Parameters such as demographic information, characteristics of burn injury, C-reactive protein, fibronectin, transferrin and prealbumin were evaluated.

Interventions

OTHERBurn Physiotherapy Protocol

It consisted of parameters such as early mobilisation and ambulatory training, chest physiotherapy, and both active and passive normal joint movement exercises.

Study design

Allocation

NON_RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to 47 Years

Healthy volunteers

Inclusion criteria

* Age ≥ 18 years * Major burn injury (according to ABA) * Conscious patients

Exclusion criteria

* Inhalation injury * Various chronic disorders * Organ dysfunctions

Design outcomes

Primary

Measure	Time frame	Description
Fibronectin	Changes in fibronectin at 6 weeks later	Blood test
Prealbumin	Changes in prealbumin at 6 weeks later	Blood test
C-reactive protein	Changes in C-reactive protein at 6 weeks later	Blood test
Transferrin	Changes in transferrin at 6 weeks later	Blood test

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026