Nutritional and Metabolic Disease
Conditions
Keywords
antioxidant capacity
Brief summary
The objective of the present study was to evaluate the impact of a snack bar on some health indicators associated with diet (plasma antioxidant capacity, lipid profile, vitamin A profile (retinol and carotenoids)) and on the nutritional status (impact on energy and nutrients consumed) in a group of upper level students.
Detailed description
A blind randomized controlled clinical study of healthy adults, which was carried out with the approval of the ethics committee of the Centro de Investigación en Alimentación y Desarrollo, A.C. (CIAD, A.C.) with registration CE/001/2017. The intervention was carried out in a public university in Mexico from January to April 2017. Each subject signed an informed consent form. This study lasted 30 days (4 weeks), where each participant consumed daily a snack bar irradiated with UV-C. The participants were personally interviewed by the research team with a structured selection questionnaire. Thirty subjects who met the inclusion criteria were recruited, 15 of them men and 15 women. Through a simple randomization process, the participants were assigned in 3 groups of 10 people each with 5 women and 5 men, subsequently treatments (without treatment, pineapple snack bar, or mango snack bar) were randomly assigned. The outcomes between groups were analyzed with one way ANOVA, with a P-value of 0.05 or less when there was statistical significance, using statistical software. The participants, and the laboratory technicians were blinded to the treatment assignments until the conclusion of the trial.
Interventions
OTHERNo Intervention
This gruop did not have an intervention
DIETARY_SUPPLEMENTPineapple snack bar
30 g daily of pineapple snack bar
DIETARY_SUPPLEMENTMango snack bar
30 g daily of mango snack bar
Sponsors
Universidad de Sonora
Centro de Investigación en Alimentación y Desarrollo A.C.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Young adults of 18 years of age or older, * Healthy in appearance
Exclusion criteria
* People in current medical treatment * Used antibiotics in past 15 days * Have presented infectious symptoms on previous days * Smokers * Narcotic consumers * Women in use of hormonal treatment * Contraceptives or pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change Oxygen Radical Absorbance Capacity Assay (Antioxidant Capacity) | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Trolox Equivalent Antioxidant Capacity (Antioxidant Capacity) | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Serum Retinol Determination | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Serum pro-VA carotenoids | Change from baseline at thirty days | From baseline and thirty days post treatment |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change Body Mass Index | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Body composition by fat-free mass index | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Serum total polyphenols determination | Change from baseline at thirty days | From baseline and thirty days post treatment |
| 24-hour dietary recall | Baseline and thirty days | From baseline and thirty days post treatment |
| Change Body composition by fat mass index | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Serum cholesterol determination | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Serum Triacylglycerides determination | Change from baseline at thirty days | From baseline and thirty days post treatment |
| Change Serum high density lipoprotein cholesterol | Change from baseline at thirty days | From baseline and thirty days post treatment |
Outcome results
None listed