Metabolic Surgery
Conditions
Keywords
metabolic surgery, metabolic disease
Brief summary
Metabolic surgery, as a recognition treatment option for patients with clinical morbid obesity, is gaining increasing appreciation. In addition to substantial weight loss, emerging studies have highlighted that metabolic surgery can substantially ameliorate obesity-related metabolic diseases, including but not limited to type 2 diabetes mellitus (T2DM), hypertension, dyslipidemia, obstructive sleep apnea-hypopnea syndrome (OSAHS) and polycystic ovary syndrome (PCOS)in severely obese patients. However, further investigations with larger sample size and longer observation time still needed to clarity the efficacy and safety of metabolic surgery in Chinese patients with obesity and encouraging future research in this field.
Interventions
None listed
Sponsors
Beijing Friendship Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* be able to receive metabolic surgery (LSG or LRYGB)
Exclusion criteria
* can not be able to understand and willing to participate in this registry with signature
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| the excess weight loss effect of metabolic surgery after 1year | 1 year after surgery | Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| the adverse events rate of metabolic surgery | 30 days after surgery | show the surgical safety by 30 days follow-up according to guideline（such as: bleeding, leak, obstruction, re-operation for complication） |
| the excess weight loss effect of metabolic surgery with long-time follow-ups | 3 years | Percent excess weight loss (%EWL), %EWL=\[(initial weight)-(post-op weight)\]/\[(initial weight)-(ideal weight)\] (in which ideal weight is defined by the weight corresponding to a BMI of 25 kg/m2) |
| the glycemic control effect of metabolic surgery with long-time follow-ups | 3 years | the decrease of HbA1c, glucose level, C-peptide and insulin levels |
| the glycemic control effect of metabolic surgery after 1 year | 1 year after surgery | the decrease of HbA1c, glucose level, C-peptide and insulin levels |
Countries
China
Contacts
Primary ContactZhongtao Zhang, M.D.
Backup ContactMengyi Li, M.D.
Outcome results
None listed