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Implementation of Finnish Prehospital Stroke Scale to Emergency Medical Services

Implementation of Finnish Prehospital Stroke Scale (FPSS) to Emergency Medical Services - a Prospective, Multi-centre Study

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03520335
Enrollment
200
Registered
2018-05-09
Start date
2018-04-24
Completion date
2021-12-31
Last updated
2020-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Recognition of Thrombectomy Candidate

Keywords

stroke, conjugated eye deviation, prehospital, stroke scale, large vessel occlusion

Brief summary

The investigators have developed a simple prehospital stroke scale (FPSS), containing 5 dichotomized items to recognize both large and small artery thrombi of the brain. FPSS is implemented to both emergency medical services and later, to emergency response centers. The efficacy of the scale and possible improvement of both the patient flow and treatment results will be evaluated.

Detailed description

Finnish Prehospital Stroke Scale, FPSS, was developed for prehospital setting for prediction of large vessel occlusions (LVOs) and stroke in common. It contains four stroke signs used universally in emergency medical services (EMSs) and emergency response centers (ERCs): 1) facial weakness, 2) extremity weakness, 3) speech disturbance, 4) visual disturbance. Additionally, it contains only one item 5) conjugated gaze deviation, while all the items are presented in dichotomized form. In an earlier, retrospective cohort of 856 code stroke patients, the sensitivity of FPSS for LVOs was highest for thrombi of areas with the documented cost effectiveness of endovascular treatment: internal carotid artery (ICA) and M1 segment of middle cerebral artery (72 % and 82 %). The overall specificity of FPSS for the LVOs was 91 %. For its simplicity it is easy to implement in EMS and ERC as a single score predicting both thrombolysis and thrombectomy candidates. In the present study accuracy of FPSS will be studied prospectively. FPSS is launched 5/18 in EMS in an area with a population of more than a million, containing districts of five central hospitals capable for thrombolysis and one university hospital capable for endovascular treatment. During 2019-20 FPSS will be launched in two ERCs triaging stroke patients in the study area. The hypotheses that are tested are: 1. FPSS is accurate to detect ICA and M1 thrombi in EMS setting 2. The use of FPSS shortens door-in-door-out (DIDO) delay patients arriving to central hospitals and redirected to university hospital for thrombectomy. 3. The use of FPSS aids to triage LVO-patients straight to a center capable for thrombectomy 4. FPSS is accurate in the detection of ICA and M1 thrombi in ERC setting 5. The effect of fluent triage of LVO is seen in overall shortened recanalization delay and better outcomes as lower modified Rankin Scores (mRS) in 3 months control compared recanalization delays and 3 month mRS during the pre-implementation period.

Interventions

None listed

Sponsors

Central Finland Hospital District
CollaboratorOTHER
Vaasa Central Hospital, Vaasa, Finland
CollaboratorOTHER
Seinajoki Central Hospital
CollaboratorOTHER
Satakunta Central Hospital
CollaboratorOTHER
PaijatHame Central Hospital
CollaboratorOTHER
Tampere University Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Acute ischaemic stroke * Prehospital susipicion of large vessel occlusion

Exclusion criteria

\- Stroke mimic

Design outcomes

Primary

MeasureTime frameDescription
Accuracy3 yearsAccuracy of Finnish Prehospital Stroke Scale used in prehospital settingto detect a large vessel occlusion Finnish Prehospital Stroke Scale (FPSS) includes the following items: Facial droop 0-1, Weakness of one or more extremities 0-1, Difficulty of understand or produce speech, including slurring 0-1, Field cut of visus or blindness 0-1, Partial or fixed gaze or head deviation away from the paretic side 0 or 4. Total points 1-4 predicts non-LVO, ≥ 5 predicts LVO 0-8 (non-LVO= small or medium-sized vessel occlusion; iv-thrombolysis candidate; LVO= large vessel occlusion; endovascular treatment candidate)

Secondary

MeasureTime frameDescription
90 day survival3 years90 day survival
90 day modified Rankin score3 years90 day modified Rankin score
Onset to treatment time3 yearsOnset to treatment time

Countries

Finland

Contacts

Primary ContactSatu-Liisa K Pauniaho, MD, PhD
satu-liisa.pauniaho@pshp.fi+358505386783
Backup ContactJyrki P Ollikainen, MD
jyrki.ollikainen@pshp.fi+358331166067

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026