Substance Use Disorders
Conditions
Keywords
Employment
Brief summary
Addiction is a chronic relapsing disorder. High magnitude and long-duration voucher-based abstinence reinforcement is one of the most effective treatments for alcohol and drug addiction and can maintain abstinence over extended periods of time, but practical methods of implementing these interventions are needed. Workplaces could be ideal and practical vehicles for arranging and maintaining abstinence reinforcement over long time periods. Investigators' research on a model Therapeutic Workplace has shown that employment-based abstinence reinforcement, in which participants must provide alcohol- or drug-free urine samples to maintain maximum pay, can maintain alcohol and drug abstinence. Now investigators need to develop effective and economically sound methods to arrange long-term exposure to employment-based abstinence reinforcement. Investigators are proposing to evaluate the effectiveness and economic benefits of a Wage Supplement Model of arranging long-term exposure to employment-based abstinence reinforcement. Under this model, successful Therapeutic Workplace participants are offered abstinence-contingent wage supplements if they obtain and maintain competitive employment. Governments have used wage supplements effectively to increase employment in welfare recipients. The Wage Supplement Model harnesses the power of wage supplements to promote employment, while simultaneously using the wage supplements to reinforce drug and alcohol abstinence. The intervention will combine 3 elements -- the Therapeutic Workplace, Individual Placement and Support (IPS) supported employment, and abstinence-contingent wage supplements. IPS is a supported employment intervention that has been proven effective in promoting employment in adults with severe mental illness. Under this model, participants will be exposed to the Therapeutic Workplace to initiate abstinence and establish job skills. To promote employment and prevent relapse to drug use, participants will receive IPS Plus Abstinence-Contingent Wage Supplements. A randomized trial will evaluate the effectiveness and economic benefits of the Abstinence-Contingent Wage Supplement Model in promoting employment and sustaining drug abstinence. Participants will be enrolled in the Therapeutic Workplace for 3 months and then randomly assigned to a Usual Care Control group or an IPS Plus Abstinence-Contingent Wage Supplement group for one year. Usual Care Control participants will be offered counseling and referrals to employment and treatment programs. IPS Plus Abstinence-Contingent Wage Supplement participants will receive the IPS intervention and abstinence-contingent wage supplements. This novel intervention could be an effective and economically sound way to promote long-term employment and drug abstinence.
Interventions
Participants are offered abstinence-contingent wage supplements if they obtain and maintain competitive employment. The wage supplements are designed to promote employment while reinforcing drug abstinence. To help participants obtain and maintain competitive employment, participants will receive Individual Placement and Support (IPS) supported employment. IPS is a supported employment intervention that has been proven effective in promoting employment in adults with severe mental illness. To promote employment and prevent relapse to drug use, participants will receive IPS Plus Abstinence-Contingent Wage Supplements.
Sponsors
Study design
Eligibility
Inclusion criteria
* 18 years or older * meet Diagnostic and Statistical Manual (DSM-V) criteria for substance use disorder * interested in obtaining employment
Exclusion criteria
* suicidal or homicidal ideation * meet Diagnostic and Statistical Manual (DSM-V) criteria for psychotic disorder
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Alcohol Abstinence | 1 year | Percentage of participants abstinent per month |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Employment | 1 year | Percentage of participants employed per month |
Countries
United States
Participant flow
Recruitment details
Participants were recruited from treatment clinics and recovery houses serving adults with alcohol use disorder, online job boards, and through compensated referrals by participants. Participants were recruited from 2 January 2019 through 5 March 2020 and from 29 October 2020 through 12 May 2022. The pause in recruitment was due to regional and institutional restrictions related to the COVID-19 pandemic. Most of the study was conducted remotely because of the COVID-19 pandemic.
Pre-assignment details
This was a two-group randomized clinical trial. All participants completed a 1-month Phase 1 Induction and Initiation period and were then randomly assigned to an intervention or control group. After random assignment, participants completed a 6-month Phase 2 Intervention period and completed study assessments every month.
Participants by arm
| Arm | Count |
|---|---|
| IPS Plus Abstinence-Contingent Wage Supplement Abstinence-contingent wage supplements are provided for obtaining and maintaining competitive employment.
IPS Plus Abstinence-Contingent Wage Supplement: Participants are offered abstinence-contingent wage supplements if they obtain and maintain competitive employment. The wage supplements are designed to promote employment while reinforcing drug abstinence. To help participants obtain and maintain competitive employment, participants will receive Individual Placement and Support (IPS) supported employment. IPS is a supported employment intervention that has been proven effective in promoting employment in adults with severe mental illness. To promote employment and prevent relapse to drug use, participants will receive IPS Plus Abstinence-Contingent Wage Supplements. | 62 |
| Usual Care Control Counseling and referrals to employment and treatment programs. | 57 |
| Total | 119 |
Baseline characteristics
| Characteristic | IPS Plus Abstinence-Contingent Wage Supplement | Total | Usual Care Control |
|---|---|---|---|
| Age, Continuous | 39.2 years STANDARD_DEVIATION 7.7 | 39.4 years STANDARD_DEVIATION 8.1 | 39.6 years STANDARD_DEVIATION 8.5 |
| Race (NIH/OMB) American Indian or Alaska Native | 0 Participants | 1 Participants | 1 Participants |
| Race (NIH/OMB) Asian | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Black or African American | 19 Participants | 43 Participants | 24 Participants |
| Race (NIH/OMB) More than one race | 0 Participants | 0 Participants | 0 Participants |
| Race (NIH/OMB) Native Hawaiian or Other Pacific Islander | 1 Participants | 1 Participants | 0 Participants |
| Race (NIH/OMB) Unknown or Not Reported | 0 Participants | 1 Participants | 1 Participants |
| Race (NIH/OMB) White | 42 Participants | 73 Participants | 31 Participants |
| Region of Enrollment United States | 62 Participants | 119 Participants | 57 Participants |
| Sex: Female, Male Female | 10 Participants | 18 Participants | 8 Participants |
| Sex: Female, Male Male | 52 Participants | 101 Participants | 49 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 0 / 62 | 0 / 57 |
| other Total, other adverse events | 0 / 62 | 0 / 57 |
| serious Total, serious adverse events | 3 / 62 | 3 / 57 |
Outcome results
Alcohol Abstinence
Percentage of participants abstinent per month
Time frame: 1 year
Population: Intent to treat
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| IPS Plus Abstinence-Contingent Wage Supplement | Alcohol Abstinence | 82.8 percentage of participants |
| Usual Care Control | Alcohol Abstinence | 60.2 percentage of participants |
Employment
Percentage of participants employed per month
Time frame: 1 year
Population: intent-to-treat
| Arm | Measure | Value (NUMBER) |
|---|---|---|
| IPS Plus Abstinence-Contingent Wage Supplement | Employment | 51.3 percentage of participants |
| Usual Care Control | Employment | 31.6 percentage of participants |