Rupture, Spontaneous, Rupture Liver, Hepatocellular Carcinoma
Conditions
Keywords
Partial hepatectomy, Emergency, Staged, Peritoneal dissemination, Propensity score matching
Brief summary
To investigate the best treatment for hepatocellular carcinoma rupture
Detailed description
To investigate the best treatment for hepatocellular carcinoma rupture, transcatheter arterial embolization or partial hepatectomy. Furthermore, to discuss the choice of emergency or staged hepatectomy.
Interventions
PROCEDUREPartial hepatectomy
Partial hepatectomy was comprised of single or multiple liver resections aiming to excise all macroscopic tumors.
Sponsors
Huazhong University of Science and Technology
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
15 Years to 76 Years
Healthy volunteers
No
Inclusion criteria
* Being diagnosed as hepatocellular carcinoma with tumor rupture; with complete data and without loss of follow-up
Exclusion criteria
* Without complete data; with loss of follow-up; not hepatocellular carcinoma based on pathological diagnosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Overall survival of all patients | 5 years | Overall survival difference between the partial hepatectomy group and the non-surgical group |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Recurrence-free survival of all patients | 5 years | Recurrence-free survival difference between the partial hepatectomy group and the non-surgical group |
| Overall survival of partial hepatectomy patients | 5 years | Overall survival difference between the emergency partial hepatectomy group and the staged partial hepatectomy group |
| Postoperative peritoneal dissemination | 5 years | Postoperative peritoneal dissemination diagnosed by imaging examination |
| Overall survival of staged partial hepatectomy patients | 5 years | Overall survival difference between the staged early partial hepatectomy group and the staged late partial hepatectomy group |
| Recurrence-free of staged partial hepatectomy patients | 5 years | Recurrence-free survival difference between the staged early partial hepatectomy group and the staged late partial hepatectomy group |
| Recurrence-free survival of partial hepatectomy patients | 5 years | Recurrence-free survival difference between the emergency partial hepatectomy group and the staged partial hepatectomy group |
Outcome results
None listed