Myopia
Conditions
Brief summary
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
Detailed description
1.The primary objective of the current study is to investigate changes in uncorrected visual acuity, diopter, accommodation, peripheral refraction, IOP, tear film quality, corneal thickness, corneal topography, corneal biomechanical parameters, objective optical quality, corneal and conjunctiva sensitivity and choroidal thickness for children with different diopters after wearing orthokeratology lenses; 2. Through measure long-term changes of these parameters, including corneal topography, axial length, peripheral refraction, objective optical quality and choroidal thickness, to explore occurrence and development regularity of myopia.
Interventions
None listed
Sponsors
Shanghai Eye Disease Prevention and Treatment Center
Study design
Observational model
CASE_ONLY
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
8 Years to 15 Years
Healthy volunteers
Yes
Inclusion criteria
* 1\. subjects were 6-16 years of age; 2.had no other ocular diseases aside from refractive error and no keratoconus (confirmed by pre-treatment corneal topography); 3. had an intraocular pressure (IOP) of \<21 mmHg; 4. had an with-the- rule astigmatism (axes 180 ± 30) ≤ 1.50 D; 5.had a best corrected visual acuity（BCVA） ≤0.00 log MAR units in both eyes (Snellen equivalent to 20/20);
Exclusion criteria
* 1\. had binocular vision problems; 2.use medications that might affect refractive development; 3.had history of ortho-k or contact lens wear; 4. Ocular surface diseases and other eye diseases which can cause abnormalities of ocular surface; 5. Patients with histories of ocular injury or surgery; 6. Corneal staining and decentration of lens after wearing Ortho-k.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| axial length measured by IOL-master | 2 years | measured by IOL-master |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| corneal thickness measured by Corvis-ST | 2 years | measured by Corvis-ST |
| corneal biomechanical parameters measured by Corvis-ST | 2 years | measured by Corvis-ST |
| tear film quality measured by Keratography | 2 years | measured by Keratography |
| accommodation measured by open field auto ref/keratometer measurements(WAM-5500,Grand Seiko) | 2 years | measured by open field auto ref/keratometer measurements(WAM-5500,Grand Seiko) |
| IOP measured by Corvis-ST | 2 years | measured by Corvis-ST |
| corneal morphological characteristics measured by Optikon 2000 corneal topographer | 2 years | measured by Optikon 2000 corneal topographer |
| objective optical quality measured by OQAS visual quality analyzing system | 2 years | measured by OQAS visual quality analyzing system |
| corneal and conjunctiva sensitivity measured by Cochet-Bonnet | 2 years | measured by Cochet-Bonnet |
| choroidal thickness measured by ocular coherence tomography | 2 years | measured by ocular coherence tomography |
| peripheral refraction measured by open field auto ref/keratometer measurements(WAM-5500,Grand Seiko) | 2 years | measured by open field auto ref/keratometer measurements(WAM-5500,Grand Seiko) |
Countries
China
Contacts
Primary ContactZhu Mengjun, MD
Outcome results
None listed