Blood Pressure, Exercise Capacity, Respiratory Muscle, Sympathetic Nerve Activity
Conditions
Brief summary
The investigators seek to understand how reflexes from the breathing muscles influence blood pressure during exercise. Furthermore, the investigators are determining if increasing breathing muscle strength (via inspiratory muscle training) influences the respiratory muscle contribution to blood pressure during exercise.
Interventions
OTHERInspiratory Muscle Training (IMT)
Inspiratory muscle training (IMT) are breathing exercises used to increase strength and endurance of the respiratory muscles.
OTHERNo Inspiratory Muscle Training (IMT)
No inspiratory muscle training.
Sponsors
National Heart, Lung, and Blood Institute (NHLBI)
Mayo Clinic
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
Healthy participants with no history of cardiovascular, pulmonary, neurologic, orthopedic or other neuromuscular diseases.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| VO2 max test | Through study completion, an average of one year. | Using a MedGraphics metabolic cart, the investigators will measure the maximum amount of oxygen that an individual can utilize during exercise. During this test the subject will be asked to exercise to his/her max capacity on a recumbent bicycle while breathing through a mouth piece that is hooked into the MedGraphics computer software. |
| Blood Pressure | Through study completion, an average of one year. | Blood pressure will be taken every few minutes during exercise testing using a standard blood pressure cuff to monitor changes in blood pressure. |
Countries
United States
Outcome results
None listed