Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT03514251

Enrollment

400

Registered

2018-05-02

Start date

2018-04-01

Completion date

2018-09-30

Last updated

2018-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complication of Surgical Procedure, Hypoparathyroidism, Marker; Structural, Parathyroid Function Low Adverse Event, Thyroid Cancer

Keywords

Thyroid Cancer, Hypoparathyroidism, parathyroid marker

Brief summary

To study the protective effect of suture parathyroid marker method on the function of parathyroid gland in thyroid cancer surgery

Detailed description

This is a prospective randomized controlled study.In the experimental group, the suture parathyroid marker method was used to mark the parathyroid gland at the first time when it shows, and this marker was further used to identify and locating the inferior parathyroid marker in subsequent central region dissection. In the control group, the central area was routinely cleaned without suture parathyroid marker .

Interventions

PROCEDUREThe suture marks the location of the parathyroid gland

When the lower parathyroid gland is first seen, the parathyroid gland is sutured with a suture during the operation, and then during this subsequent cleaning, rapid parathyroid localization and parathyroid glands are performed through this marker. Vascular protection.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Inclusion criteria

* Patients with thyroid cancer who need central compartment dissection * Routine neck incision surgery * Patients undergoing primary neck surgery

Exclusion criteria

* Benign thyroid tumor patients * Selecting patients with endoscopes, small incisions, or robotic surgery * Patients with hyperparathyroidism

Design outcomes

Primary

Measure	Time frame	Description
The stitch marking operation time	During surgery	The time required for making a parathyroid marker by a suture method
Specimen inspection time	During surgery	The time required for finding parathyroid glands in surgical specimens
The number of transplanted parathyroid glands	When the surgery is completed	The number of parathyroid glands required for autotransplantation of parathyroid glands
Parathyroid hormone level testing	0 days, 1 day, 2 weeks after surgery	Parathyroid hormone levels before and after surgery
Calcium levels	0 days, 1 day, 2 weeks after surgery	Calcium level before and after surgery to detect

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026