NMO Spectrum Disorder;Registry Study
Conditions
Brief summary
In 1894, Devic first proposed the concept of neuromyelitis optica(NMO). NMO is an inflammatory demyelinating disease that selectively affects the central nervous system of the optic nerve and spinal cord.In 2004, Lennon and other persons found highly specific AQP4（aquaporin 4）antibodies in NMO patients'sera, and further differentiated between NMO and MS, confirming that NMO is an independent disease.At present, NMO has been widely recognized as an idiopathic and severe demyelinating disease of the central nervous system.In 2015, the international NMO diagnostic team developed the diagnostic criteria based on highly specific AQP4 antibodie.Up to now, in China, there is no data on the number of NMOSD patients, the rate of misdiagnosis, the treatment methods, and the prognosis.This study is committed to build China's NMOSD big data platform to provide the basis for diagnosis, treatment and prognosis of the disease.
Interventions
DIAGNOSTIC_TESTserum AQP4-antibody testing method
there are different methods of testing serum AQP4-antibody
Sponsors
Beijing Tongren Hospital
Study design
Observational model
OTHER
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
14 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. more than 14 years old 2. Compliance with the diagnostic standard by the NMO International Diagnostic team in 2015
Exclusion criteria
1. less than 14 years old 2. NOT Compliance with the diagnostic standard by the NMO International Diagnostic team in 2015
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| misdiagnosis rate | 3 years | misdiagnosis rate of NMOSD |
Countries
China
Outcome results
None listed