Acute Kidney Injury After Cardiac Surgery on CPB

Incidence of Acute Kidney Injury After Cardiac Surgery on Cardiopulmonary Bypass in the Pediatric Intensive Care Unit of Lausanne. A Retrospective Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT03513718

Enrollment

250

Registered

2018-05-01

Start date

2017-10-01

Completion date

2023-09-05

Last updated

2024-02-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Kidney Injury, CBP, Child, Only, Congenital Heart Disease, Surgery

Keywords

Acute kidney injury, AKI

Brief summary

The purpose of this retrospective study is to determine the incidence and severity of acute kidney injuries (AKI) after heart surgery on cardiopulmonary bypass (CPB) in the pediatric intensive care unit (PICU) in Lausanne, Switzerland.

Detailed description

The investigators will review in a retrospective way, all patients aged between 0 and 16 years, admitted in the PICU after cardiac surgery on CPB from 01.01.2014 to 31.12.2016. They will asses for AKI. The first step is to determine the incidence and severity, the second step is to determine the risk factors for AKI and/or protecting factors.

Interventions

None listed

Study design

Observational model

OTHER

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

No minimum to 16 Years

Healthy volunteers

Yes

Inclusion criteria

\- all pediatric patients (0-16 years) admitted to PICU after cardiac surgery with CPB.

Exclusion criteria

* Preexisting kidney injury, * no preoperative creatinine lab value

Design outcomes

Primary

Measure	Time frame	Description
Presence and severity of an AKI occurring during stay in the PICU	up to 3 month	Scoring AKI with pRiffle

Secondary

Measure	Time frame	Description
PICU stay and ventilation time	up to 3 month	correlation between AKI and invasive ventilation/duration and PICU stay
Persisting AKI after release from PICU according to RIFLE score	more than 3 month	After leaving ICU

Countries

Switzerland

Outcome results