Echocardiography, Heart Failure, Heart Failure Acute
Conditions
Keywords
acute heart failure, global longitudinal strain, ejection fraction, echocardiography, mortality
Brief summary
STRATS-AHF (STrain for Risk Assessment and Therapeutic Strategies in patients with Acute Heart Failure) registry enrolled 4,312 patients hospitalized for acute HF from 3 tertiary university hospitals (Seoul National University Bundang Hospital, Seoul National University Hospital, and Chungnam National University Hospital) from January 2009 through December 2016.
Detailed description
Patients with signs or symptoms of heart failure and either lung congestion, or objective findings of left ventricular (LV) systolic dysfunction or structural heart disease, were eligible for the study. Echocardiography was performed and both LV ejection fraction (LVEF) and LV global longitudinal strain (LV-GLS), right ventricular GLS (RV-GLS) were measured.
Interventions
1. Measurement of left ventricular ejection fraction and global longitudinal strain 2. Measurement of left atrial reservoir strain (peak atrial longitudinal strain) 3. Measurement of right ventricular global longitudinal strain
Sponsors
Study design
Eligibility
Inclusion criteria
* Patients with signs or symptoms of HF and either lung congestion, or objective findings of LV systolic dysfunction or structural heart disease
Exclusion criteria
* Patients who presented with acute coronary syndrome
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| All-cause mortality | up to 5 years | Death from any cause |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hospitalization for heart failure | up to 5 years | Any hospitalization for acute heart failure after the index hospitalization |
| Composite of all-cause mortality and hospitalization for heart failure | up to 5 years | Death from any cause or any hospitalization for acute heart failure after the index hospitalization |
| Ischemic stroke | up to 5 years | Ischemic stroke (an episode of neurological dysfunction caused by embolism) after the index hospitalization |
Countries
South Korea