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Strain for Risk Assessment and Therapeutic Strategies in Patients With Acute Heart Failure (STRATS-AHF) Registry

Strain for Risk Assessment and Therapeutic Strategies in Patients With Acute Heart Failure (STRATS-AHF) Registry

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT03513653
Acronym
STRATS-AHF
Enrollment
4312
Registered
2018-05-01
Start date
2009-01-01
Completion date
2023-12-31
Last updated
2023-04-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Echocardiography, Heart Failure, Heart Failure Acute

Keywords

acute heart failure, global longitudinal strain, ejection fraction, echocardiography, mortality

Brief summary

STRATS-AHF (STrain for Risk Assessment and Therapeutic Strategies in patients with Acute Heart Failure) registry enrolled 4,312 patients hospitalized for acute HF from 3 tertiary university hospitals (Seoul National University Bundang Hospital, Seoul National University Hospital, and Chungnam National University Hospital) from January 2009 through December 2016.

Detailed description

Patients with signs or symptoms of heart failure and either lung congestion, or objective findings of left ventricular (LV) systolic dysfunction or structural heart disease, were eligible for the study. Echocardiography was performed and both LV ejection fraction (LVEF) and LV global longitudinal strain (LV-GLS), right ventricular GLS (RV-GLS) were measured.

Interventions

DIAGNOSTIC_TESTEchocardiography with speckle-tracking imaging

1. Measurement of left ventricular ejection fraction and global longitudinal strain 2. Measurement of left atrial reservoir strain (peak atrial longitudinal strain) 3. Measurement of right ventricular global longitudinal strain

Sponsors

Seoul National University Bundang Hospital
CollaboratorOTHER
Chungnam National University Hospital
CollaboratorOTHER
Seoul National University Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients with signs or symptoms of HF and either lung congestion, or objective findings of LV systolic dysfunction or structural heart disease

Exclusion criteria

* Patients who presented with acute coronary syndrome

Design outcomes

Primary

MeasureTime frameDescription
All-cause mortalityup to 5 yearsDeath from any cause

Secondary

MeasureTime frameDescription
Hospitalization for heart failureup to 5 yearsAny hospitalization for acute heart failure after the index hospitalization
Composite of all-cause mortality and hospitalization for heart failureup to 5 yearsDeath from any cause or any hospitalization for acute heart failure after the index hospitalization
Ischemic strokeup to 5 yearsIschemic stroke (an episode of neurological dysfunction caused by embolism) after the index hospitalization

Countries

South Korea

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 26, 2026