Multiple Sclerosis
Conditions
Keywords
Multiple sclerosis, Multi-task training, Balance, Mobility, Cognition, Upper extremity function
Brief summary
The Activities of Daily Living requires the ability to perform multiple activities at the same time, not just the motor or cognitive activity. When many tasks are performed at the same time, the attention capacity is effectively used and attention is shared according to the difficulty and priority of the tasks. There is evidence that patients with Multiple Sclerosis (MS) have reduced performance during multitasking. In this study, the investigators aim to investigate the effect of multitasking training on balance, mobility, upper extremity performance and cognitive functions in patients with MS.
Detailed description
Patients with MS between 0-1,5 score according to the Extended Disability Status Scale (EDSS) will be included in the study. The balance, mobility, upper extremity performance, the cognitive function will be evaluated twice. The study was designed as a prospective, randomized controlled study. The patients will be randomly assigned to three groups, the multi-task training (MT) group, the single task training (ST) group, and control group. The training will be twice a week for 6 weeks. Statistical analyses will be performed using the SPSS software version 15 (SPSS Inc. Chicago, IL, USA). The pre-training and post-training measurements of groups will be compared with the Wilcoxon Test. The significance level was set at p\< 0.05
Interventions
OTHERMulti-task training
In the multitasking training group, a second motor task in the first two weeks, a cognitive task in the third and fourth week, both motor and cognitive tasks in the last two weeks will be added to these 10 different motor tasks.
OTHERSingle task training
An exercise program consisting of 10 different motor tasks will be implemented in a single task training group.
Sponsors
Gazi University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Participants who are ambulatory and volunteer to participate to the study, in a stable phase of the disease, without relapses in the last 3 month, with an EDSS between 0-1,5.
Exclusion criteria
* Participants who have orthopedic, vision, hearing, or perception problems * Patients who have any cardiovascular or pulmonary disease in which exercise is contraindicated
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mobility | ten minutes] | Timed Up and Go Test |
| Modified Sensory Organization Test | Fifteen minutes] | The Modified Sensory Organization Test, which is performed using computerized posturography, measures postural sway in response to 4 different sensory conditions is measured using a force platform. |
| Upper extremity function | ten minutes | 9-Hole Peg Test |
| cognitive function | thirty minutes | The Brief Repeatable Battery of Neuropsychological Tests |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physical Activity | ten minutes | International Physical Activity Questionnaire- Long version |
| Neuropsychological Questionnaire | one minute | Multiple Sclerosis Neuropsychological Questionnaire - MSNQ |
| Fatigue Impact | five minutes | Fatigue impact scale consists of forty questions and evaluates the effects of fatigue on the 3 dimensions of daily life activities; cognitive function, physical function and psychosocial function. Each question is graded between 0 (no problem) and 4 (maximum problem). |
| Fatigue Severity | Five minutes | In the Fatigue Severity Scale (FSS), participants are asked to rate their fatigue level between 1 and 7 in the 9 statements (including motivation, exercise, physical functioning, carrying out duties, and interfering with work, family, or social life) during the last week. |
| Balance Confidence | five minutes | Activities-specific Balance Confidence (ABC) is a scale in which the patient rates his perceived level of confidence while performing 16 daily living activities. |
Countries
Turkey (Türkiye)
Outcome results
None listed